Héctor J. Pula

Dr. Héctor J. Pula

orcid

Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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12 January 2022 in Animals
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FMFederico Melenchón
Federico Melenchón
EMEduardo de Mercado
Eduardo de Mercado
HPHéctor J. Pula
Héctor J. Pula
GCGabriel Cardenete
Gabriel Cardenete
FBFernando Barroso
Fernando Barroso
CTCristina Tomás-Almenar
Cristina Tomás-Almenar
The demand of optimal protein for human consumption is growing. The Food and Agriculture Organization (FAO) has highlighted aquaculture as one of the most promising alternatives for this protein supply gap due to the high efficiency of fish growth. However, aquaculture has been facing its own sustainability problem, because its high demand for protein has been traditionally satisfied with the use of fishmeal (FM) as the main source. Some of the most promising and sustainable protein substitutes for FM come from insects. The present manuscript provides insight into an experiment carried out on rainbow trout (Oncorhynchus mykiss) with a 50% replacement of FM with different larvae insect meals: Hermetia illucens (HI), and Tenebrio molitor (TM). TM showed better results for growth, protein utilization and more active digestive function, supported by intestinal histological changes. Liver histology and intermediary metabolism did not show relevant changes between insect meals, while other parameters such as antioxidant enzyme activities and tissue damage indicators showed the potential of insect meals as functional ingredients.

1 February 2018 in Aquaculture
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Journal Article
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HPHéctor J. Pula
Héctor J. Pula
CTCristina E. Trenzado
Cristina E. Trenzado
SGSergio García-Mesa
Sergio García-Mesa
CFCesar Fallola
Cesar Fallola
ASAna Sanz
Ana Sanz

2 March 2023 in Applied Sciences
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FGFrancisco Ortega García
Francisco Ortega García
María Ángeles Martín-LaraMaría Ángeles Martín-Lara
María Ángeles Martín-Lara
HPHéctor J. Pula
Héctor J. Pula
Montserrat ZamoranoMontserrat Zamorano
Montserrat Zamorano
Mónica Calero de HocesMónica Calero de Hoces
Mónica Calero de Hoces
Gabriel Blázquez GarcíaGabriel Blázquez García
Gabriel Blázquez García
This research aims to develop a new strategy to valorize wasted COVID-19 masks based on chemical recycling by pyrolysis to convert them into useful products. First, surgical and filtering face piece masks, as defined in Europe by the EN 149 standard (FFP2), were thermally pyrolyzed at temperatures of 450, 500, and 550 °C, and the yields of valuable solid (biochar), liquid (biooil), and syngas products and their characteristics were determined. At low temperatures, biochar formation was favored over biooil and syngas production, while at high temperatures the syngas product yield was enhanced. The highest yield of biooil was found at a pyrolysis temperature of 500 °C, with both surgical and FFP2 masks achieving biooil yields of 59.08% and 58.86%, respectively. Then, the pyrolysis experiments were performed at 500 °C in a two-stage pyrolysis catalytic reactor using sepiolite as a catalyst. Sepiolite was characterized using nitrogen adsorption–desorption isotherms and Fourier-transform infrared spectroscopy. Results showed that the two-stage process increased the final yield of syngas product (43.89% against 39.52% for surgical masks and 50.53% against 39.41% for FFP2 masks). Furthermore, the composition of the biooils significantly changed, increasing the amount of 2,4-Dimethyl-1-heptene and other olefins, such as 3-Eicosene, (E)-, and 5-Eicosene, (E)-. Additionally, the methane and carbon dioxide content of the syngas product also increased in the two-stage experiments. Ultimately, the effect of sepiolite regeneration for its use in consecutive pyrolysis tests was examined. Characterization data showed that, the higher the use-regeneration of sepiolite, the higher the modification of textural properties, with mainly higher changes in its pore volume. The results indicated that the pyrolysis of face masks can be a good source of valuable products (especially from biooil and syngas products).

18 February 2013 in Environmental Toxicology
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AOA. L. Oropesa
A. L. Oropesa
BJB. Jiménez
B. Jiménez
MGM. C. Gil
M. C. Gil
JOJ. Osswald
J. Osswald
CFC. Fallola
C. Fallola
LGLuis Gomez
Luis Gomez

13 February 2023 in Applied Sciences
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JBJuan Jesús de la Torre Bayo
Juan Jesús de la Torre Bayo
María Ángeles Martín-LaraMaría Ángeles Martín-Lara
María Ángeles Martín-Lara
Mónica Calero de HocesMónica Calero de Hoces
Mónica Calero de Hoces
PCPedro Miguel Sánchez Castillo
Pedro Miguel Sánchez Castillo
HPHéctor J. Pula
Héctor J. Pula
Montserrat ZamoranoMontserrat Zamorano
Montserrat Zamorano
Using a science mapping approach, we analyzed the exponential increase in the number of scientific documents about the negative environmental impacts produced by waste from personal protective equipment (PPE), especially face masks, used to reduce SARS-CoV-2 transmission worldwide. Our results revealed that India, China, and Canada are leaders in this research field, which is clearly related to environmental issues, but also the solutions developed from an engineering point of view. Our analysis of the most-relevant documents in the field uncovered the considerable negative effects of PPE waste in aquatic media, its contribution to greenhouse gas emissions, effects on wildlife, etc. To reduce the negative environmental impacts of PPE waste, we need to implement innovative ecodesign strategies for their green production, including their re-use as and the use of recycling materials, but also a collaboration with the population to reduce PPE waste at its source. Both action lines could be materialized by establishing a collective, extended producer responsibility system for PPE to ensure their sustainable production and consumption. These well-implemented strategies will contribute to maintaining progress towards achieving sustainable development goals.

3 August 2025 in Marine Drugs
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MSMáximo Servillera
Máximo Servillera
MCMaría Mercedes Peña Contreras
María Mercedes Peña Contreras
LCLaura Cabeza
Laura Cabeza
HPHéctor J. Pula
Héctor J. Pula
JPJose Prados
Jose Prados
CMConsolación Melguizo
Consolación Melguizo
Nudibranchs have garnered increasing interest in biomedical research due to their complex chemical defense mechanisms, many of which are derived from their diet, including sponges, cnidarians, tunicates, and algae. Their remarkable ability to sequester dietary toxins and synthesize secondary metabolites positions them as a promising source of biologically active compounds with potential therapeutic applications, particularly in oncology. This study aimed to review and summarize the available literature on the bioactive potential of nudibranch-derived compounds, focusing mainly on their antitumor properties. Although research in this area is still limited, recent studies have identified alkaloids and terpenoids isolated from species such as Dolabella auricularia, Jorunna funebris, Dendrodoris fumata, and members of the genus Phyllidia. These compounds exhibit notable cytotoxic activity against human cancer cell lines, including those from colon (HCT-116, HT-29, SW-480), lung (A549), and breast (MCF7) cancer. These findings suggest that compounds derived from nudibranchs could serve as scaffolds for the development of more effective and selective anticancer therapies. In conclusion, nudibranchs represent a valuable yet underexplored resource for antitumor drug discovery, with significant potential to contribute to the development of novel cancer treatments.