Objective: Postnatal tissue accretion in preterm infants differs from those in utero, affecting body composition (BC) and lifelong morbidity. Length normalized BC data allows infants with different body lengths to be compared and followed longitudinally. This study aims to analyze BC of preterm and term infants during the first six months of life. Methods: The BC data, measured using dual energy X-ray absorptiometry, of 389 preterm and 132 term infants from four longitudinal studies were combined. Fat-mass/length2 (FMI) and fat-free mass/length2 (FFMI) for postmenstrual age were calculated after reaching full enteral feeding, at term and two further time points up to six months corrected age. Results: Median FMI (preterm) increased from 0.4 kg/m2 at 30 weeks to 2.5, 4.3, and 4.8 kg/m2 compared to 1.7, 4.7, and 6 kg/m2 in term infants at 40, 52, and 64 weeks, respectively. Median FFMI (preterm) increased from 8.5 kg/m2 (30 weeks) to 11.4 kg/m2 (45 weeks) and remained constant thereafter, whereas term FFMI remained constant at 11 kg/m2 throughout the tested time points. Conclusion: The study provides a large dataset of length normalized BC indices. Followed longitudinally, term and preterm infants differ considerably during early infancy in the pattern of change in FMI and FFMI for age.
The half logistic-geometric (HLG) distribution derived here is a simple distribution with interesting properties and is therefore a useful distribution for analyzing lifetime data. Algorithm is derived for the computation of single and product moments of order statistics from this distribution. These recurrence relations enable the computation of means, variances and covariances of all order statistics for all sample size in a simple and efficient way. The results are of great importance in determining the best linear unbiased estimator of the scale parameter of a scaled-HLG distribution, and those of parameters of the more general location-scale HLG distribution based on complete and Type-II censored samples. Finally, an example is presented to illustrate the developed results.
One-shot devices are products or equipments that can be used only once. A nature characteristic of one-shot devices is that they get destroyed immediately after their use, and therefore their actual lifetimes are never observable. The only information observed is the condition whether they worked or not at the time they are used. These days the quality of products are significantly improved, so that the information obtained under a normal test during a short time is quite limited. A typical test to induce more failures is the accelerated life-test, which is developed by increasing the stress levels under test. In this paper, we will investigate the reliability of one-shot devices with generalized gamma fatigue life under accelerated life-tests with various cyclic temperature fluctuations by assuming a Norris-Landzberg model. Generalized gamma involves many common lifetime distributions, such as gamma, Weibull, lognormal, and positive stable distributions, as special cases. Norris-Landzberg model takes not only temperature change, highest testing temperature, but also the cycling frequency into account when modeling the number of cycles-to-failure, resulting a generalized model with the well-known Coffin-Manson model and Coffin-Manson-Arrhenius model as special cases. Associated inferences are developed. The performance of the proposed model and inferential methods will be evaluated with simulation study and model discrimination. Finally, the chip-scale package solder joints data is analyzed to illustrate the considered model and inferential methods developed in this paper.