Sérgio Antônio Lemos De Morais

Dr. Sérgio Antônio Lemos De Morais


Research Focus & Metrics

Academic Career Length

28Years (1999-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 August 2002 in Revista Árvore
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CQCarla Regina Amorim dos Anjos Queiroz
Carla Regina Amorim dos Anjos Queiroz
SMSérgio Antônio Lemos De Morais
Sérgio Antônio Lemos De Morais
ENEvandro Afonso Do Nascimento
Evandro Afonso Do Nascimento
Visando contribuir para a caracterização química de uma madeira nobre nativa e em extinção no Brasil, no presente trabalho estão apresentados os estudos de identificação e quantificação dos taninos da aroeira-preta (Myracrodruon urundeuva), uma espécie da família Anacardiaceae. Este estudo foi conduzido com base nos extratos acetona-água (AA) e metanol-água (MA), em que foram determinados os teores de fenóis totais e proantocianidinas. O teor de fenóis totais foi determinado pelo método Folin-Ciocalteau e pelo método azul-da-prússia modificado. Os valores encontrados para os métodos AA foram 19,1 e 24,7% e para MA, 20,2 e 22,8%, respectivamente. O teor de proantocianidinas foi determinado pelo método da vanilina, tendo alcançado no extrato AA 2,7% e no MA 16,7%. Não foram constatadas as presenças de antocianidinas nem de apigedinidinas, podendo haver 3-deoxi-proantocianidinas do tipo luteolinidinas. Por meio da cromatografia líquida de alta eficiência (CLAE), foram identificados a fisetina e os ácidos gálico e elágico. Os resultados mostram que a aroeira-preta contém uma elevada quantidade de taninos, que podem contribuir para sua resistência natural à degradação.

1 June 2005 in Revista Árvore
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SMSérgio Antônio Lemos De Morais
Sérgio Antônio Lemos De Morais
ENEvandro Afonso Do Nascimento
Evandro Afonso Do Nascimento
DMDárley Carrijo de Melo
Dárley Carrijo de Melo
Neste estudo foram analisados os principais componentes químicos da madeira de Pinus oocarpa, cultivado na região do cerrado. A composição química dessa madeira foi: 59,05% de a-celulose, 21,22% de hemiceluloses A e B, 25,18% de lignina, 2,78% de extrativos em diclorometano, 4,38% de extrativos em etanol:tolueno, 4,31% de extrativos em água quente e 1,26% de cinzas. O conteúdo de celulose foi relativamente elevado, indicando que essa madeira possui grande potencial para produção de pasta de celulose. Investigou-se, também, a composição dos extrativos. Os principais constituintes do extrato diclorometano dessa madeira foram os ácidos diterpênicos, além dos ácidos palmítico e oléico. No óleo essencial, extraído por aparelho de Clevenger, os principais componentes identificados foram aromadendreno, ledano, hexadecanal e ácido oléico.

1 December 1999 in Journal of the Brazilian Chemical Society
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SMSérgio Antônio Lemos De Morais
Sérgio Antônio Lemos De Morais
ENEvandro A. Nascimento
Evandro A. Nascimento
CQCarla R.A.A. Queiroz
Carla R.A.A. Queiroz
DPDorila Piló-Veloso
Dorila Piló-Veloso
MDMariza G. Drumond
Mariza G. Drumond

1 January 2012 in Evidence-Based Complementary and Alternative Medicine
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KLK. C. Lamounier
K. C. Lamounier
LCL. C. S. Cunha
L. C. S. Cunha
SMSérgio Antônio Lemos De Morais
Sérgio Antônio Lemos De Morais
FAFrancisco Aquino
Francisco Aquino
RCR. Chang
R. Chang
WCWilson Cunha
Wilson Cunha
Maclura tinctoria(L.) D. Don ex Steud. has one of the highest qualities among the coefficients for Brazilian woods (up to 9.6) and resistance rates equivalent to Indian teak (Tectona grandis). In this study, the macromolecular constituents and total phenols compounds as well as the antioxidant and antibacterial activities of this wood were evaluated. Total phenols and proanthocyanidin levels were higher in wood when compared with bark levels. The antioxidant activity of wood extracts (IC50= 18.7 μg/mL) was more effective than that of bark extracts (IC50= 20.9 μg/mL). Wood and bark extracts revealed a high potential for inhibition of aerobic and anaerobic bacteria. The bark extracts were the most active (MIC from 20 to 60 μg/mL). Both antioxidant activity and high potential for bacteria inhibition turn these extracts promising for drug formulations, especially as antibacterial agent.

18 April 2013 in Molecules
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LCLuís C. S. Cunha
Luís C. S. Cunha
SMSérgio Antônio Lemos De Morais
Sérgio Antônio Lemos De Morais
CMCarlos Henrique Martins
Carlos Henrique Martins
MMMário M. Martins
Mário M. Martins
RCRoberto Chang
Roberto Chang
ENEvandro A. Do Nascimento
Evandro A. Do Nascimento
The chemical composition of the essential oils from leaves, bark and wood of Cassia bakeriana Craib. was determined by gas chromatography (GC) and gas chromatography–mass spectrometry (GC-MS). Alcohols, aldehydes and fatty acids were the major components in leaf and bark oil, while wood essential oil was rich in fatty acids. Terpenes such as linalool, (E)-nerolidol and phytol were present in low concentrations. The antimicrobial activity against aerobic and anaerobic oral bacteria was evaluated using the microdilution method, as was the cell viability test carried out with Vero cells. The oils from leaves and bark showed high antimicrobial activity, with minimum inhibitory concentrations between 62.5 and 125 µg·mL−1 for most of the tested bacteria, including Streptococcus mutans, the main etiological agent of dental caries. Leaves oil displayed the lowest cytotoxic effect (EC50 of 153 µg·mL−1), while wood oil exhibited the highest toxicity to Vero cells. C. bakeriana oils are thus a source of biologically active compounds against aerobic and anaerobic oral microorganisms. This study is the first report on the chemical composition, antimicrobial activity and cytotoxicity of C. bakeriana.

11 April 2014 in Molecules
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FFFabiana Barcelos Furtado
Fabiana Barcelos Furtado
FAFrancisco Aquino
Francisco Aquino
ENEvandro A. Nascimento
Evandro A. Nascimento
CMCarla De M. Martins
Carla De M. Martins
SMSérgio Antônio Lemos De Morais
Sérgio Antônio Lemos De Morais
AOAlberto De Oliveira
Alberto De Oliveira
The seasonal chemical composition of essential oils from Inga laurina was determined by GC/MS. In the stem bark’s essential oil extracted during the dry season, the presence of terpenoids (30.05%) stood out, and phytol (9.76%) was the major compound identified. For the stem bark oil obtained during the rainy season, in addition to terpenoids (26.63%), a large amount of fatty acids (46.84%) were identified, in particular palmitic acid (25.40%). Regarding the leaves’ essential oil obtained in the dry season, esters (42.35%) were the main components. The main ester present was (Z)-hex-3-enyl benzoate (10.15%) and the major compound of this oil was (Z)-hex-3-en-1-ol (14.23%). Terpenoids (33.84%), long-chain alkanes (27.04%) and fatty acids (21.72%) were the main components of the essential oil from leaves in the rainy season. Phytol (33.21%), nonacosane (21.95%) and palmitic acid (15.20%) were the major compounds identified. The antimicrobial activity against aerobic and anaerobic oral bacteria was evaluated by the microdilution broth method and cytotoxic activity was carried out with Vero cells. The essential oils from the rainy season showed a better inhibition of the bacterial growth with Minimal Inhibitory Concentrations (MIC) values of 25 or 50 µg·mL−1 for aerobic bacteria, and high selectivity against bacteria was observed. The large amount of fatty acids in rainy season oils may be related to the better inhibitory effects observed.