Megha Srivastav

Ms. Megha Srivastav

orcid

Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
29 August 2025 in Women
Verified
Journal Article
Open access
PDF file
KEKayla Ernst
Kayla Ernst
GDGabriella DaSilva
Gabriella DaSilva
MSMegha Srivastav
Megha Srivastav
ACAlexandra Campson
Alexandra Campson
PSPedro Soto
Pedro Soto
LSLea Sacca
Lea Sacca
The purpose of this scoping review is to identify major social determinants of health and barriers affecting access to mental health services in pregnant and postpartum women in the United States. It will also examine the scope of existing evidence-based interventions and dissemination and implementation strategies that were developed and implemented to increase accessibility to mental health treatment in high-risk pregnant and postpartum women. The Arksey and O’Malley Framework guided the review process, along with the Joanna Briggs Institute (JBI) recommendations for the extraction, analysis, and presentation of results in scoping reviews. Additionally, the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-SCR) was used as a reference checklist. A total of 21 studies were used for analysis that were published between 2015 and 2025. An examination of social determinants of health (SDOH) influencing factors of mental health determined that those related to neighborhood and built environment had the highest rates. Using the socioecological model, individual barriers exhibited the highest frequency, with the most common themes to these barriers across all studies being language barriers, cultural barriers, and stigma-related challenges, followed by financial and childcare challenges and transportation challenges. Major findings included important evidence that therapeutic relationships with pregnant women who are depressed can be developed and that telehealth interventions improved access for women living in rural areas. Recommendations from this review will inform evidence-based interventions to address the gap in accessibility and affordability of mental health services in US pregnant and postpartum women residing in underserved communities.

11 December 2025 in Biology
Verified
Journal Article
Open access
PDF file
IKIsabella Kirshteyn
Isabella Kirshteyn
MSMegha Srivastav
Megha Srivastav
KGKaren Grace
Karen Grace
VCVictoria Cescato
Victoria Cescato
ABAjay Bommareddy
Ajay Bommareddy
Melanoma, particularly the malignant type owing to its aggressive metastatic potential, is one of the most severe cancers. When detected early, the cure rate of melanoma is very promising and has a higher 5-year survival rate. However, it becomes very difficult to treat when it has spread to deeper layers of the skin and to other parts of the body. Despite the reduced mortality, the incidence of melanoma is on the rise due to exposure to various environmental factors, particularly UV radiation without protection. Naturally occurring dietary agents have been studied for their antitumor and chemopreventive potential against the development of various cancers including melanoma. The current review is aimed at compiling developments in the past ten years surrounding their preclinical and clinical relevance in the treatment and prevention of malignant melanoma. Various cellular pathways modulated by these phytochemicals are also examined to provide a comprehensive overview of their mechanisms involved in reducing tumor burden. Specifically, the review focuses on the most consumed foods across the world that are rich in such phytochemicals including curcumin, sulforaphane, resveratrol, quercetin and epigallocatechin gallate (EGCG) and their potential against the development of melanoma.

4 August 2026 in Pediatric Reports
Verified
Journal Article
Open access
PDF file
KLKathryn Claire Lotharius
Kathryn Claire Lotharius
KLKendell Lewis
Kendell Lewis
CPClarissa Portocarrero
Clarissa Portocarrero
MSMegha Srivastav
Megha Srivastav
SZSilvia Zervos
Silvia Zervos
LSLea Sacca
Lea Sacca
There remains a widespread lack of knowledge regarding hidradenitis suppurativa (HS) among physicians in the United States, impeding timely diagnosis and implementation of comprehensive treatment interventions. Despite the presence of supporting communities for affected adolescents and their caretakers, the overall awareness of HS remains low, and a greater consensus on the treatment of HS is needed. Current research highlights the lack of standardized pediatric guidelines for treatment of HS largely due to the varied nature of the disease and limited efficacy of current therapies. Our study aims to explore the relationship between the chronic skin condition HS and social–emotional concerns, mental health, and physical health issues in US children and adolescents. Using the Arksey and O’Malley framework and PRISMA-ScR reporting, we searched PubMed/MEDLINE, Scopus, Web of Science, Cochrane Library, and Embase for U.S. studies (2015–2025) on pediatric HS (<18 years) and social–emotional, mental health, or quality-of-life outcomes. Recommendations were synthesized, and study quality was appraised with CASP checklist methods and rigor. Ten studies (2020–2025) met inclusion criteria. Pediatric HS was associated with depression, anxiety, social withdrawal, shame, low self-esteem, and reduced quality of life. Physical comorbidities increased psychosocial burden. Socioeconomic and racial disparities worsened outcomes and access to care. Studies emphasized early diagnosis, routine screening, multidisciplinary management, and disparity-focused interventions. Findings may inform clinical practice and guide research initiatives aimed at improving outcomes for children and adolescents with HS.

7 October 2025 in Women
Verified
Journal Article
Open access
PDF file
APAvanthi Puvvala
Avanthi Puvvala
ARAtharva P Rohatgi
Atharva P Rohatgi
DLDiana Lobaina
Diana Lobaina
MSMegha Srivastav
Megha Srivastav
VJVama Jhumkhawala
Vama Jhumkhawala
LSLea Sacca
Lea Sacca
Cardiovascular disease disproportionately affects women in the United States. CVD outcomes are closely tied to a multitude of factors including lifestyle habits and socioeconomic status which create a complex interweb of determinants of health that place certain age and racial groups at higher risk over others. Such inequities highlight the need for targeted prevention strategies to address the unique risks faced by different populations. In this study, a state-wide analysis examining the mortality rates among women aged 35 years or older in Florida from 2018 to 2023 was done in order to identify high risk groups to better inform evidence-based public heath interventions that are tailored to the population’s needs. Mortality rates were extracted from the CDC Wonder Database. Age-adjusted and crude mortality rates, per 100,000 women, were calculated and stratified by ten-year age groups, Hispanic origin, race, and major CVD subtypes based on various ICD-10 codes. From the ICD-10 113 Cause List, “The Diseases of the Heart” were the cause of the majority of the deaths; however, “Other Forms of Chronic Ischemic Heart Diseases” was the leading subtype. Crude rates for the “Ischemic Heart Diseases” decreased 110.9 per 100,000 women in 2018 to 101.5 per 100,000 women in 2023. Yet, the most common cause of CVD-related mortality remains ischemic heart disease. Across the study period, non-Hispanic women experienced more than twice the crude mortality rate of Hispanic women. Racial breakdowns showed that White women had the highest CVD mortality, followed by Black women, who had elevated rates of heart failure and heart attacks in comparison to other minority groups. Asian women had the lowest rates across all cardiovascular subtypes. These findings underscore the persistent age and racial differences in cardiovascular outcomes emphasize the urgent need for culturally informed, community-specific preventative interventions to improve cardiovascular care and reduce mortality within high-risk populations.