Günay KOZAN

Dr. Günay KOZAN

orcid

Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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14 August 2023 in European Archives of Oto-Rhino-Laryngology
Verified
Journal Article
Closed access
PDF file
SCSermin Can
Sermin Can
ÖTÖmer TÜRK
Ömer TÜRK
MAMuhammed Ayral
Muhammed Ayral
GKGünay KOZAN
Günay KOZAN
HAHamza Arı
Hamza Arı
MBMüzeyyen Yıldırım Baylan
Müzeyyen Yıldırım Baylan

2 December 2023 in Brazilian Journal of Otorhinolaryngology
Verified
Journal Article
Open access
EGErhan Gökçek
Erhan Gökçek
GKGünay KOZAN
Günay KOZAN
We aimed to investigate the effect of bilateral sphenopalatine ganglion blockade (SPGB) on the main postoperative complications in septorhinoplasty operations. In this randomized, controlled, prospective study, 80 cases planned for Septorhinoplasty operations under general anesthesia were included in the study. The cases were divided into two groups; SPGB was performed with 2 mL of 0.25% bupivacaine bilaterally 15 min before the end of the operation in the SPGB group (Group S, n = 40). In the control group (Group C, n = 40), 2 mL of 0.9% NaCl solution was applied into both SPG areas. In the recovery unit after the operation; the pain and analgesic needs of the patients at 0, 2, 6 and 24 h were evaluated. There was no statistically significant difference between the groups in terms of hemodynamic parameters (ASA, MBP, HR) (p > 0.05) All VAS values were statistically lower in Group S than in Group C (p < 0.05). In Group S, the need for analgesic medication was found in 5 cases between 0-2 h, whereas in Group C, this rate was found in 17 cases, and it was statistically significant (p < 0.05). Bilateral SPGB application was determined to provide better analgesia in the early postoperative period compared to the control group, it was concluded that further studies are needed to say that there are significant effects on laryngospasm and nausea-vomiting. 2, degree of recommendation B.

24 December 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
GKGünay KOZAN
Günay KOZAN
SDSerkan Dedeoğlu
Serkan Dedeoğlu
MAMuhammed Ayral
Muhammed Ayral
MAMEHMET AKDAG
MEHMET AKDAG
Background/Objectives: Mucormycosis is a rapidly progressive invasive fungal infection that commonly involves the sinonasal region and skull base in patients with systemic comorbidities, yet robust ENT data from middle-income settings are scarce. Methods: We performed a single-center retrospective review of all patients with histopathologically confirmed mucormycosis treated in the Otorhinolaryngology Department of Dicle University between 2010 and 2023, covering a 14-year period. Eligible patients had paranasal sinus computed tomography at presentation and received surgical and/or systemic antifungal therapy. Demographic data, comorbidities, disease subtype, radiological extent, treatment modality and survival were extracted from records. Survival was estimated using Kaplan–Meier analysis, and group differences were tested with chi-square statistics (p ≤ 0.05). Results: Fifty-two patients met the inclusion criteria (mean age 56.5 ± 15.2 years; 57.7% male); 73.1% had at least one systemic comorbidity, most frequently diabetes mellitus (65.4%) and hematological malignancy (19.2%). Disease was sinonasal in 42.3%, rhino-orbital in 28.8% and rhino-orbito-cerebral in 28.8%. Baseline CT showed intracranial extension in 26.9%. Overall survival was 59.6% and differed markedly by subtype, highest in isolated sinonasal disease (81.8%) and lowest in rhino-orbito-cerebral disease (26.7%). Intracranial extension was associated with higher mortality (71.4% vs. 28.9%). Combined surgical debridement plus systemic antifungal therapy, used in 84.6% of patients, yielded lower mortality than antifungal therapy alone (31.8% vs. 87.5%). Conclusions: In this ENT cohort, prognosis was mainly determined by anatomical extent and treatment strategy. Our findings suggest that timely combined surgical and antifungal management, when feasible and in appropriately selected patients, is associated with improved survival outcomes.

8 August 2025 in Bioengineering
Verified
Journal Article
Open access
PDF file
STSerdar Ferit Toprak
Serdar Ferit Toprak
SDSerkan Dedeoğlu
Serkan Dedeoğlu
GKGünay KOZAN
Günay KOZAN
MAMuhammed Ayral
Muhammed Ayral
SCSermin Can
Sermin Can
MAMEHMET AKDAG
MEHMET AKDAG
Purpose: Mucormycosis is a life-threatening fungal infection, where rapid diagnosis is critical. We developed a deep learning approach using paranasal computed tomography (CT) images to test whether mucormycosis can be detected automatically, potentially aiding or expediting the diagnostic process that traditionally relies on biopsy. Methods: In this retrospective study, 794 CT images (from patients with mucormycosis, nasal polyps, or normal findings) were analyzed. Images were resized and augmented for training. Two transfer learning models (ResNet50 and ConvNeXt Small) were fine-tuned to classify images into the three categories. We employed a 70/30 train-test split (with five-fold cross-validation) and evaluated performance using accuracy, precision, recall, F1-score, and confusion matrices. Results: The ConvNeXt Small model achieved 100% accuracy on the test set (precision/recall/F1-score = 1.00 for all classes), while ResNet50 achieved 99.16% accuracy (precision ≈0.99, recall ≈0.99). Cross-validation yielded consistent results (ConvNeXt accuracy ~99% across folds), indicating no overfitting. An ablation study confirmed the benefit of transfer learning, as training ConvNeXt from scratch led to lower accuracy (~85%) Conclusions: Our findings demonstrate that deep learning models can accurately and non-invasively detect mucormycosis from CT scans, potentially flagging suspected cases for prompt treatment. These models could serve as rapid screening tools to complement standard diagnostic methods (histopathology), although we emphasize that they are adjuncts and not replacements for biopsy. Future work should validate these models on external datasets and investigate their integration into clinical workflows for earlier intervention in mucormycosis.

5 November 2025 in Medicina
Verified
Journal Article
Open access
PDF file
SDSerkan Dedeoğlu
Serkan Dedeoğlu
GKGünay KOZAN
Günay KOZAN
MAMuhammed Ayral
Muhammed Ayral
BKBetül Dertsiz Kozan
Betül Dertsiz Kozan
Background and Objectives: Lateral osteotomies in rhinoplasty run adjacent to the lacrimal drainage system (LDS), risking postoperative tearing. Piezoelectric (piezo) devices enable precise bone cuts that may reduce LDS trauma. We compared the 1-month incidence of objective lacrimal dysfunction after piezo versus classic osteotomy. Materials and Methods: Retrospective, single-center controlled cohort (1 January 2024–1 January 2025) at a tertiary ENT clinic. Consecutive patients aged 19–45 with pre-operative paranasal sinus CT and no prior lacrimal disorder were grouped by osteotomy technique (piezo vs. classic; n = 65 per arm). Assessments were performed at postoperative day 7–10 and at 1, 3, and 6–12 months. The primary endpoint was 1-month objective lacrimal dysfunction, defined as fluorescein dye disappearance test (FDDT) grade ≥1 or reflux/resistance on irrigation plus symptoms (Munk ≥2). Pre-specified statistical tests were used. Results: Early tearing favored piezo. At week 1, epiphora occurred in 32.3% with piezo versus 46.1% with classic (p = 0.041); by month 6, rates were 4.6% versus 15.1% (p = 0.031). Differences at months 1 and 3 also favored piezo but were not statistically significant (p = 0.062 and p = 0.088). FDDT positivity was lower with piezo at week 1 (23.0% vs. 38.4%, p = 0.045) and month 6 (3.0% vs. 10.7%, p = 0.048). Irrigation obstruction was less frequent with piezo at week 1 (7.6% vs. 21.5%, p = 0.026), but groups converged by months 1 (15.4% vs. 12.3%, p = 0.80) and 3 (6.2% vs. 4.6%, p > 0.99). Punctum stenosis/occlusion remained uncommon in both groups without significant differences. Conclusions: Piezo-assisted lateral osteotomy is associated with less early lacrimal dysfunction and lower 6-month epiphora compared with the classic technique. Convergence of irrigation findings by 1–3 months suggests postoperative edema as the dominant transient mechanism. Given the retrospective, single-center design and low event rates, multicenter prospective studies powered for early LDS outcomes are warranted.

15 July 2025 in Journal of Craniofacial Surgery
Verified
Journal Article
Closed access
RGRecep Gokce
Recep Gokce
SDSerkan Dedeoğlu
Serkan Dedeoğlu
TKTayyar Kilinç
Tayyar Kilinç
SSSerhat Samanci
Serhat Samanci
GKGünay KOZAN
Günay KOZAN
STSerdar Ferit Toprak
Serdar Ferit Toprak
Background: Tracheostomy in pediatric intensive care units (PICU) is an important procedure that has become increasingly common in the last decade, reflecting advances in neonatal and pediatric intensive care. Methods: Main clinical diagnoses were grouped according to the organ system involved. Indications for tracheostomy were defined as the main reason for performing a tracheostomy. Patients were categorized into 4 categories according to the indications for tracheostomy. Namely, airway anomalies (AA), central nervous system (CNS) diseases, cardiopulmonary insufficiency (CPI), and neuromuscular diseases (NMD). Results: Nontraumatic neurological diseases were present in 30 patients (43.4%), genetic or metabolic diseases in 15 (21.7%), infection and sepsis in 9 (13%), malignancy in 6 (8.6%), cardiorespiratory disorders in 5 (7.2%), and trauma in 4 (5.7%). In group analysis, there was no difference in the frequency of early and late problems between newborns and older children. Conclusion: The timing of tracheostomy in the PICU is an important factor that has a significant impact on patient outcomes. The available literature provides valuable insight into the potential benefits of early tracheostomy in improving outcomes in critically ill pediatric patients.