Bogdan Enache

Dr. Bogdan Enache

orcid

Research Focus & Metrics

Academic Career Length

18Years (2009-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 June 2018 in Circulation: Arrhythmia and Electrophysiology
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Journal Article
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RARuben Casado Arroyo
Ruben Casado Arroyo
DLDecebal Gabriel Laţcu
Decebal Gabriel Laţcu
SMShingo Maeda
Shingo Maeda
MKMaciej Kubala
Maciej Kubala
PSPasquale Santangeli
Pasquale Santangeli
FMFrancis E. Marchlinski
Francis E. Marchlinski
Background: The electrocardiographic and intracardiac activation features of left atrial roof-dependent macroreentrant flutter have been incompletely characterized. Methods: Patients post–pulmonary vein (PV) isolation with roof-dependent atrial flutter based on activation and entrainment mapping were included. ECG and coronary sinus activation were compared with mitral annular (MA) flutter. Results: The roof-dependent left atrial flutter circled the right PVs in 32 of 33 cases. Two forms of roof flutters were identified, posteroanterior, ascendant on posterior wall and descendant on anterior wall (n=24); and anteroposterior, ascendant on the anterior wall and descendent on the posterior wall (n=9). Both forms had positive large amplitude P waves in V 1 through V 2 with decreasing amplitude in V 3 through V 6 . Posteroanterior roof flutters had positive P wave in the inferior and negative P wave in leads I and aVL similar to counterclockwise MA flutter, but coronary sinus activation was simultaneous for roof and proximal to distal for counterclockwise. Anteroposterior roof flutters were similar to clockwise MA flutter with negative P in inferior leads and transition to flat or negative P in V 3 through V 6 . Coronary sinus activation time ≤39 ms identified roof versus MA flutter (sensitivity: 100% and specificity: 97%). Conclusions: Roof-dependent flutter around right PVs is more common than around left PVs. The ECG pattern for roof-dependent flutter around right PVs is similar to MA flutter with frontal plane axis dictated by septal activation. Roof-dependent flutter can be distinguished from MA flutter by more simultaneous rather than sequential coronary sinus activation.

1 January 2019 in EP Europace
Verified
Journal Article
Closed access
DLDecebal Gabriel Laţcu
Decebal Gabriel Laţcu
SBSok-Sithikun Bun
Sok-Sithikun Bun
RARuben Casado Arroyo
Ruben Casado Arroyo
AWAhmed Moustfa Wedn
Ahmed Moustfa Wedn
FBFatima Azzahrae Benaich
Fatima Azzahrae Benaich
NSNadir Saoudi
Nadir Saoudi
Successful catheter ablation of scar-related atrial tachycardia depends on correct identification of the critical isthmus. Often, this is a represented by a small bundle of viable conducting tissue within a low-voltage area. It's identification depends on the magnitude of the signal/noise ratio. Ultra-high density mapping, multipolar catheters with small (eventually unidirectional) and closely-spaced electrodes improves low-voltage electrogram detection. Background noise limitation is also of major importance for improving the signal/noise ratio. Electrophysiological properties of the critical isthmus and the characteristics of the local bipolar electrograms have been recently demonstrated as hallmarks of successful ablation sites in the setting of scar-related atrial tachycardia.

1 August 2015 in Clinical Interventions in Aging
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Journal Article
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RSRaluca Sosdean
Raluca Sosdean
CMCristian Mornos
Cristian Mornos
BEBogdan Enache
Bogdan Enache
RMRazvan Macarie
Razvan Macarie
RIRaluca Ianos
Raluca Ianos
SPSorin Pescariu
Sorin Pescariu
Introduction: Cardiac resynchronization therapy (CRT) is known to have very important beneficial effects on heart failure patients. Unfortunately, biventricular implantable cardiac devices (CRT devices), through which this therapy is implemented, are very expensive and sometimes hard to achieve, especially in underdeveloped/developing economies, making this an important problem of public health. As a possible solution, CRT reuse is of great interest nowadays, but unlike simple devices, data in the literature are scarce about biventricular device reuse. Aim: To address safety concerns, we aimed to analyze infection burden in the general and elderly population and also early battery depletion and generator malfunction of resterilized biventricular devices compared to new devices. Methods: A cohort of 261 CRT patients (286 devices), who underwent implantation between 2000 and 2014, was retrospectively analyzed. The study group included 115 patients and 127 resterilized devices, that was divided into a subgroup of 69 elderly patients (≥60 years) and 74 devices and a subgroup of 47 younger patients (<60 years) and 53 devices, and the control group included 146 patients and 159 new devices. The groups were compared using a multivariate logistic regression model. Results: A number of 12 (4.2%) infectious complications were encountered, five (3.9%) in the study group and seven (4.4%) in the control group (odds ratio, 2.83 [0.59–13.44], P=0.189), one (1.3%) in the elderly and four (7.5%) in the younger subgroup (odds ratio, 3.80 [0.36–40.30], P=0.266), with no statistically significant difference between them. There was only one case of early battery depletion, after 17 months, in one study group patient. No generator malfunction was detected. Conclusion: Reuse of biventricular cardiac implantable electronics seems feasible and safe in both the general population and the elderly population, and it could be a promising alternative when new devices cannot be obtained in a safe period of time.

13 June 2019 in Pacing and Clinical Electrophysiology
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Journal Article
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BEBogdan Enache
Bogdan Enache
R(Raluca Coifan (Șoșdean)
Raluca Coifan (Șoșdean)
RMRăzvan Macarie
Răzvan Macarie
BDBernard Dodinot
Bernard Dodinot
SPSorin Pescariu
Sorin Pescariu

12 June 2020 in Clinical Research in Cardiology
Verified
Journal Article
Open access
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BEBogdan Enache
Bogdan Enache
YCYann-Erick Claessens
Yann-Erick Claessens
FBFabrice Boulay
Fabrice Boulay
VDVincent Dor
Vincent Dor
AEArmand Eker
Armand Eker
APAtul Pathak
Atul Pathak

15 March 2019 in Clinical Cardiology
Verified
Journal Article
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SBSOK-SITHIKUN BUN
SOK-SITHIKUN BUN
PTPhilippe Taghji
Philippe Taghji
AEAbdelkarim Errahmouni
Abdelkarim Errahmouni
DLDecebal Gabriel Laţcu
Decebal Gabriel Laţcu
AAAlaa Al Amoura
Alaa Al Amoura
NSNadir Saoudi
Nadir Saoudi
Background: Echocardiography realization can be challenging in the presence of breasts implants (BI). It is less known if electrocardiograms (ECG) may be modified in the presence of BI.Methods: ECG from women with BI (and without any known cardiac structural disease) were sent and analyzed by two experienced electrophysiologists (EP1 and EP2) who were blinded and completely unaware of the context of the patients (Group 1). ECG from a control matched‐group of female women without BI (Group 2) were also blindly sent for analysis.Results: ECG were collected from 28 women with BI (42 ± 8 years) without any acute medical condition. A proportion of 42% of the ECG were considered abnormal by EP1 and 46% by EP2. The abnormalities were for EP1: negative T waves (5), ST depression in inferolateral leads (2), absence of R wave progression from V1 to V4 (4), left ventricular (LV) hypertrophy (1), long QT(1), early repolarization (1), short PR (1); For EP2: negative T waves (6), ST depression in inferolateral leads (2), absence of R wave progression from V1 to V4 (4), LV hypertrophy(3), long QT (1), early repolarization (1). ECG from group 2 were considered abnormal in only 1 patient (5%) for EP1, and normal in all for EP2 (P = 0.0002 between the groups).Conclusions: ECG from women with BI were considered abnormal in 42% to 46% of the cases by expert readers. ECG interpretation can thus be misleading in these women.