The nonlinear dynamic responses of a wire rope under periodic excitation in a friction hoisting system are investigated. Longitudinal excitation experiments of different periodic excitation frequencies are performed. The nonlinear dynamic characteristics of the rope, including transverse, longitudinal, and coupled vibrations, are discussed with time-frequency analysis. The results show that the transverse vibration is a forced vibration following the excitation, while the longitudinal vibration shows a complex, random vibration state. The vibration amplitude and intensity deviate significantly from their linear trend (superharmonic resonance) at some excitation frequencies, and this deviation indicates the typical nonlinear multiorder natural frequency characteristics. The lifting motion can lead to additional corrugated high-order harmonics and cause a fundamental wave distortion of low-frequency excitation. Experimental evidence for the coupling characteristics of the transverse-longitudinal rope vibration in the lifting process is found.

A new transmission theory of “global dynamic wrap angle” for friction hoist is proposed. The theory is based on a mine hoist simulation model which combines the suspended rope with the wrapped rope. Rope dynamics in a suspended section are verified by the field experiment results. The theory holds that the mechanical state of wire rope is dynamic through the whole wrap angle, including deformation, contact and friction. When the rope enters the wrap angle, it provides positive friction and changes direction at a certain boundary point. The demarcation of the boundary depends on the rope load on both sides of the friction pulley. The theory is suitable for accurately analyzing the kinetics of high-speed and heavy-load friction hoisting.

Sim, a potent HMG-CoA reductase inhibitor, exhibits notable anabolic effects on bone and can upregulate osteogenic genes such as BMP-2, thereby promoting bone formation. An ideal drug delivery system for Sim involves its controlled and sustained release at the defect site to minimize adverse side effects. In this study, Sim was first modified via HP-γ-CD to form a hydrophilic Sim/HP-γ-CD inclusion complex, thereby improving drug solubility and dispersion in aqueous systems. A gelatin–sodium alginate (Gel/SA) hydrogel was then employed as the drug delivery matrix to construct a Gel-SA-Sim/HP-γ-CD hydrogel sustained release system. This hydrogel system exhibited a high water content (82%), along with enhanced mechanical properties, including a compressive strength of 0.284 MPa and a compressive modulus of 0.277 MPa, suggesting strong load-bearing capacity and favorable stiffness. Importantly, Sim was released in a controlled and sustained manner over 7 days, without exhibiting burst release behavior. In vitro osteogenic differentiation assays demonstrated that optimal concentrations of Sim effectively enhanced cellular bioactivity and osteoinductive performance, offering a promising approach to enhance the bioactivity, osteogenesis, and osseointegration of orthopedic implants.