Dramatic natural events recently stroke several countries worldwide. The impact of the natural events on industrial sites often resulted in large releases of hazardous materials, causing severe technological accidents (Natural-Technological or NaTech events). Industrial operators were often found unprepared or off-guard for unannounced events but also when they had received early warnings. Due to these occurrences, public awareness has raised and the issue of NaTech is now considered as an emerging risk. Due to the climate change and increase in the frequency of some categories of natural disasters, the likelihood of NaTech scenarios is growing, thus NaTech may be also considered as a new risk in some areas of the world. In the present study, the process that ended in the awareness of the scientific community and of the general public toward NaTech has been analyzed. Available tools and knowledge gaps in the assessment of NaTech scenarios are evidenced. The analysis is mainly addressed to the potential impact of flood, lightning, and earthquake events on industrial installations where hazardous substances are present, aiming at the identification of strategies to improve the resilience of industrial facilities to technological accidents caused or intensified by natural hazards.