A humanização em saúde é um passo de extrema importância para os atendimentos, visto que qualquer situação que envolva a falta de saúde nos torna vulneráveis em relação à vida. Mesmo quando o quadro parece ser apenas de natureza orgânica, tudo que acontece impacta nosso ser integralmente, trazendo consequências sociais, espirituais, físicas, emocionais e econômicas em maior ou menor grau. Quando em tratamento, nossa adesão e confiança dependerão da equipe que cuida e é nesse aspecto que muitos estudos mostram que a relação paciente-família com a equipe é tão importante quanto a qualidade do tratamento técnico-científico prestado. O presente artigo traz algumas reflexões sobre o cuidado em saúde, especialmente sobre o paradigma biopsicossocial que visa superar o paradigma curativista ou biomédico, se refletindo nas transformações no conceito de saúde e na compreensão no processo saúde-doença. Para tanto, o presente trabalho traz como objetivo discutir a integralidade como eixo norteador na formação de profissionais de saúde. A pesquisa bibliográfica para responder as questões foram procuradas nas seguintes bases de dados: BDTD (Biblioteca digital brasileira de teses e dissertações), CINAHL (Cumulative Index to nursing and allied health literature), LILACS (Literatura Latino-americana e do Caribe em ciências da saúde), MedLine (Literatura Internacional em ciência da Saúde), PAHO (Biblioteca da Organização Pan-Americana da Saúde) e SciELO (Scientific Electronic Library Online). A transição de um conceito biomédico de saúde para um biopsicossocial, implica uma série de reconfigurações nos sentidos de saúde-doença-cura, do tratar-cuidar, bem como de noções de saúde coletiva e sua inclusão com a comunidade, mas se torna necessário para atender o ser humano como um ser completo em todas as esferas de sua vida e tal aprendizado deve ser perpetuado desde os cursos de formação em saúde.

Introduction: Oral health care directly impacts the well-being of incarcerated women. It is related to the quality of life, social and economic discrepancies and lack of access to programs that offer free dental services and health promotion for this population. Objectives: This work aimed to understand oral health challenges faced by women incarcerated in Brazil and worldwide. Material and method: The following databases were selected: EMBASE, (Virtual Health Library=LILACS+BDENF), Scielo, Scopus, Cochrane-Library and the PubMed search engine. These databases were searched until the closing date of October 2021 with no time limit for the searches. The key words used in the searches were “incarceration”, “prison”, “woman”, and “oral health”. Results: Caries, periodontal disease, tooth pain, and the use of dental prostheses were the most prevalent oral health conditions amongst incarcerated women in Brazil and worldwide. Regarding the level of scientific evidence, the included articles fit level III, according to Melnyk and Fineout. Discussion: Bearing in mind the limitations of the study, oral diseases in the global context showed that the quality of life related to oral and systemic health of women during and after incarceration was negatively affected. It is also essential for further clinical and follow-up studies to be carried out on incarcerated women that address their actual oral health needs.

Aim: Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ) plays important anti-inflammatory roles, including in periodontitis. This systematic review with a meta-analysis compiles evidence on the transcriptional and translational levels of PPAR-γ in clinical and experimental periodontitis studies, alongside functional enrichment and PPAR-γ interaction network analyses. Method: Electronic searches were conducted in six databases for publications up to February 2024. For the meta-analysis of experimental studies of periodontitis, PPAR-γ levels in the periodontal tissues were assessed through gene expression (RT-qPCR) or protein expression (Western blotting). In the clinical periodontitis studies, PPAR-γ levels in the gingival tissues were evaluated through protein expression (immunohistochemistry). A risk of bias (RoB) assessment was performed using the Systematic Review Centre for Laboratory Animal Experimentation (SYRCLE) and Newcastle Ottawa Scale (NOS) tools for experimental and clinical studies, respectively. The enrichment analysis was performed using the g:Profiler tool, and gene interaction networks were analyzed using GeneMANIA. Results: The meta-analysis demonstrated significantly lower PPAR-γ protein levels in the periodontal tissues from animals with periodontitis. PPARG mRNA and PPAR-γ quantification through immunohistochemistry remained inconclusive. The bioinformatics analyses indicated direct or indirect PPAR-γ-associated molecules involved in the immune response to periodontitis. The PPAR-γ protein expression was higher in periodontal tissues from healthy animals compared to that from those with periodontitis. Conclusions: Given the inconclusive findings of RT-qPCR and immunohistochemistry, further PPARG mRNA and PPAR-γ protein evaluations are needed to clarify their levels in the periodontal tissues.

Introduction and objective: the WHO defined the concept of quality of life as the self-perception that the individual has about his position in the social, cultural and ideological context, being these factors the main responsible for denoting the worst parameters regarding oral health care during the dental clinical examination performed by the dentist. To evaluate the impact of oral health on the quality of life of children with special health care needs aged 7 to 14 years old and the influence of different types of specialties on the quality of life, in the view of parents/caregivers in the Brazil southeast region. Materials and methods: the sample was composed of 62 children enrolled in municipal public schools and the Association of Parents and Friends of the Exceptional. The validated Parental- Caregivers Perception Questionnaire (P-CPQ) was used as an instrument for data collection, applied in the home environment and answered by the main responsible. The relation between demographic factors, type of special need and P-CPQ was evaluated with alpha of 0.05. Results: the worst parameters in Family Impact Scale were observed when the mother and father was responsible for data transmission (p= 0.004). Oral health was associated with the worst parameters of oral symptoms on quality of life in the view of parents (p = 0.012). There was no statistically significant difference regarding the impact of the child's type of specialty on quality of life. Conclusion: the variables caregiver and oral health status child are related to the worst indicators regarding the impact of oral health on quality of life.

This study aimed to perform an integrative review of the literature on the use of silicone finger prostheses in amputee patients. Searches were performed in the PubMed, EMBASE, Web of Science, Scielo, and Cochrane Library databases until July 2021. Descriptors used in this article were: Silicone, finger, rehabilitation, and prosthesis. Clinical research and clinical reports on silicone finger prostheses, available in full and in English were included. Initially, 152 articles were identified. After establishing the inclusion/exclusion criteria, 23 studies were identified and constituted the final sample. Regarding the publication date of the included studies, 17.2% of them were published between 2012 and 2016. Most of the rehabilitations occurred in India (69.9%; n = 16), and the mean age of patients who used prostheses was 38.1 years. The level of scientific evidence of the included studies was IV and VI. Therefore, patients rehabilitated with silicone finger prostheses highlighted significant improvements in functional range of motion, restoration of self-esteem, advantages in psychological therapy, more pleasant social interaction, and changes in their quality of life.