Background: Cutaneous melanoma is the leading cause of skin cancer-related mortality, and early detection is crucial to improving prognosis. Teledermatology (TD) has increasingly been adopted in melanoma care to address growing demand and limited access to specialists. This systematic review aimed to evaluate the role of TD in the diagnosis and management of suspected melanoma under real-world clinical conditions. Methods: The review was conducted and reported in accordance with the PRISMA 2020 guidelines. Literature searches were performed in PubMed, Embase, Web of Science, and Scopus up to December 2024. Studies assessing TD use in routine practice were included, focusing on diagnostic accuracy, prognostic indicators, waiting times, satisfaction, and economic outcomes. Results: TD showed high sensitivity and specificity, particularly when dermoscopic images and expert interpretation were available. Some studies reported reduced Breslow thickness and shorter delays compared to face-to-face care. Overall satisfaction was high among both patients and clinicians. Economic evaluations suggested potential cost savings, although formal analyses were limited. The use of artificial intelligence tools yielded mixed results and was generally perceived with caution in the absence of clinical supervision. Conclusions: Teledermatology appears to be a useful approach for improving access and supporting early diagnosis in melanoma care. Its effectiveness depends on proper implementation and integration into clinical workflows.

Advances in the understanding of atopic dermatitis (AD) pathogenesis have driven the development of innovative systemic therapies targeting key immunologic pathways. This systematic review summarizes current evidence on the impact of biologic agents, Janus kinase (JAK) inhibitors, and other emerging treatments on AD-related biomarkers and their correlation with clinical outcomes. A comprehensive literature search was conducted across PubMed, Embase, Scopus, and Web of Science for studies published between 2014 and 2024. Eighty studies met the inclusion criteria. Dupilumab was the most extensively investigated therapy, followed by tralokinumab, JAK inhibitors, and novel agents such as amlitelimab, stapokibart, and tezepelumab. Across drug classes, consistent reductions in CCL17/TARC, LDH, and total IgE levels were observed, generally paralleling clinical improvement in EASI and SCORAD scores. Transcriptomic and proteomic analyses revealed normalization of Th2/Th22 inflammatory signatures and restoration of barrier-related gene expression, while microbiome studies showed a reduction in Staphylococcus aureus colonization. Despite these advances, the heterogeneity of study designs and analytical techniques limits the comparability of results. CCL17 and LDH currently represent the most reliable biomarkers associated with disease severity and treatment response, although their limited specificity restricts clinical applicability. Future research should aim to validate integrated biomarker panels combining immunologic, transcriptomic, and microbiomic data to enable precision medicine approaches in atopic dermatitis management.

Objetivo principal: analizar la investigación enfermera en la producción científica del Área Sanitaria de Ferrol (ASF). Metodología: estudio descriptivo en el que se utilizó Sophos, base de datos de producción científica del Servicio Gallego de Salud para la recogida de datos. En enero de 2022, se realizó una exportación a Excel de los autores clasificados como personal de enfermería del ASF y de su producción científica en el periodo 2011-2020. Resultados principales: se identificaron 78 autores: el 24,35% trabaja en atención primaria y el 75,65% en atención hospitalaria. Se contabilizaron 169 publicaciones, clasificadas en estas categorías: artículos originales, artículos de opinión, artículos de revisión, comunicaciones a congresos, guías y otro tipo de documentos, repartidas entre 50 revistas. Se distinguen 8 redes de colaboración que publican el 82,24% de los artículos, frente al 17,75% publicado por un único autor. Conclusión principal: el análisis de las redes de colaboración muestra equipos de enfermería consolidados que colaboran tanto dentro del ASF como con otros centros del Sergas y otro personal enfermero completamente integrado en equipos de investigación de sus servicios. Objective: To analyse nursing research in the scientific production of the Ferrol Health Area (ASF). Methods: A descriptive study in which Sophos, the scientific production database of the Galician Health Service, was used for data collection. The authors were classified as nursing staff of the ASF and their scientific production from 2011 to 2020 was exported into an Excel spreadsheet in January 2022. Results: 78 authors were identified: 24.35% work in primary care and 75.65% in hospital care. A total of 169 publications were identified, classified as: original articles, opinion articles, review articles, communications to congresses, guidelines and other types of documents; and distributed among 50 journals. Eight collaborative networks were identified, publishing 82.24% of the articles compared to 17.75 % published by a single author. Conclusions: The analysis of the collaboration networks shows consolidated nursing teams that collaborate both within the ASF and with other Sergas centres and other nursing staff fully integrated with research teams in their services.