The present study aims to evaluate the antioxidant activity of tomato powders obtained from whole tomatoes of three local cultivars—Andrada, Hera, and Kristinica—using the Ferric Reducing Antioxidant Power (FRAP) assay. The cultivars were grown in open fields without additional treatments or fertilizer application. Ascorbic acid was used as a reference antioxidant standard. Results indicated that Andrada powder exhibited the highest antioxidant activity, at 248.1 ± 5.3 µmol Fe²⁺/100 g, followed by Hera (235.6 ± 4.9 µmol Fe²⁺/100 g) and Kristinica (212.8 ± 5.1 µmol Fe²⁺/100 g), while ascorbic acid, used as a positive control, showed the highest overall antioxidant capacity (260.0 ± 4.5 µmol Fe²⁺/100 g). The high lycopene and flavonoid content of the analyzed powders supports their potential as functional ingredients in food applications and their use in horticulture. This research is particularly relevant as it promotes a sustainable approach for the utilization of tomato products, aligning with the principles of circular agriculture.