Perfusion assessment is critical in clinical oncology, particularly in tumor characterization, intraoperative decision making, and postoperative outcome predictions. Hyperspectral imaging (HSI) has emerged as a promising, non-contact, non-invasive, and contrast-free modality capable of capturing spatial and spectral information related to tissue oxygenation and hemoglobin distribution. This study provides an up-to-date review of recent advances in the use of HSI for perfusion monitoring in clinical oncological applications, with a special focus on its adoption in laparoscopic surgeries, brain tumor delineation, and head and neck cancer interventions. The integration of HSI into surgical workflows and its potential to reduce complications are discussed. Overall, while HSI is emerging as an appealing, real-time, quantitative perfusion imaging modality, a lack of standardized protocols and interpretation guidelines pose the most significant challenges. Addressing these gaps through multicenter clinical trials is essential for advancing the routine use of HSI in oncological surgery.
We use optical tweezers based on time-multiplexed acousto-optic deflectors to trap ultracold cesium atoms in one-dimensional arrays of atomic ensembles. For temperatures between and we study the maximal time between optical tweezer pulses that retains the number of atoms in a single trap. This time provides an estimate of the maximal number of sites in an array of time-multiplexed optical tweezers. We demonstrate evaporative cooling of atoms in arrays of up to 25 optical tweezer traps and the preparation of atoms in a box potential. Additionally, we demonstrate three different protocols for the preparation of atomic-ensemble arrays by transfer from an expanding ultracold atomic cloud. These result in the preparation of arrays of up to 74 atomic ensembles consisting of atoms on average.