The paper presents deriving of shape asymmetry measure in the dermatological sense (DASMShape). The skin lesion symmetry consists of three factors: shape, hue/color and structure. We analyze the shape asymmetry and on its basis we propose a new asymmetry degree realized in several ways. DASMShape methods verification and comparison is performed using PH2 database. The results received after optimization of the DASMShape algorithm are tested on PH2 dataset and discussion about their accuracy is provided. These results shows bigger overestimation than underestimation tendency results. DASMShape measure and its results are the initial points to derive dermatological asymmetry measure.

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