Hyperspectral images (HSIs), with their rich spectral information, are widely used in remote sensing; yet the inherent trade-off between spectral and spatial resolution in imaging systems often limits spatial details. Single-image hyperspectral super-resolution (HSI-SR) seeks to recover high-resolution HSIs from a single low-resolution input, but the high dimensionality and spectral redundancy of HSIs make this task challenging. In HSIs, spectral signatures and spatial textures often exhibit intrinsic symmetries, and preserving these symmetries provides additional physical constraints that enhance reconstruction fidelity and robustness. To address these challenges, we propose the Dynamic Spectral Collaborative Super-Resolution Network (DSCSRN), an end-to-end framework that integrates physical modeling with deep learning and explicitly embeds spatial–spectral symmetry priors into the network architecture. DSCSRN processes low-resolution HSIs with a Cascaded Residual Spectral Decomposition Network (CRSDN) to compress redundant channels while preserving spatial structures, generating accurate abundance maps. These maps are refined by two Synergistic Progressive Feature Refinement Modules (SPFRMs), which progressively enhance spatial textures and spectral details via a multi-scale dual-domain collaborative attention mechanism. The Dynamic Endmember Adjustment Module (DEAM) then adaptively updates spectral endmembers according to scene context, overcoming the limitations of fixed-endmember assumptions. Grounded in the Linear Mixture Model (LMM), this unmixing–recovery–reconstruction pipeline restores subtle spectral variations alongside improved spatial resolution. Experiments on the Chikusei, Pavia Center, and CAVE datasets show that DSCSRN outperforms state-of-the-art methods in both perceptual quality and quantitative performance, achieving an average PSNR of 43.42 and a SAM of 1.75 (×4 scale) on Chikusei. The integration of symmetry principles offers a unifying perspective aligned with the intrinsic structure of HSIs, producing reconstructions that are both accurate and structurally consistent.