Background: Polycystic ovary syndrome (PCOS) is an endocrine disorder characterized by hyperandrogenism, irregular ovulation, and polycystic ovarian morphology. The severity of periodontal inflammation in PCOS may be linked to elevated levels of inflammatory mediators, like interleukins (IL-6, IL-17), and matrix metalloproteinase-8 (MMP-8), found in both serum and saliva samples. This systematic review aims to assess the presence, nature, and variations in salivary inflammatory biomarkers in individuals with PCOS and their potential connection to periodontal disease (PD). Materials and Methods: Selected databases were PubMed, Scopus, Google Scholar, and Web of Science. The search strategy included the following terms: “oral inflammatory biomarkers”, “Salivary mediators,” “metabolic indicators,” “periodontal diseases,” “periodontitis,” “polycystic ovary syndrome,” “PCOS,” and “ovulatory dysfunction.” Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were used. Results: Several salivary inflammatory biomarkers are present in women with PCOS, including cytokines, C-reactive protein (CRP), reactive oxygen species (ROS), MMPs, and microbial diversity alterations. Additionally, the reviewed studies suggest a correlation between PCOS and PD, as patients with PCOS exhibit greater periodontal alterations compared to healthy women. The heightened periodontal response in PCOS appears to be associated with a systemic inflammatory state, probably increasing the susceptibility to PD. Conclusions: Salivary inflammatory biomarkers in PCOS patients are a useful diagnostic tool for evaluating the heightened risk of periodontal disease. Further research with stricter protocols is necessary to better define the diagnostic potential of these biomarkers for PCOS patients and determine their role in the early detection of periodontal disease.

In recent years, scientific literature has been focusing on the study of the Canalis Sinuosus (CS); this canal contains the anterior superior alveolar nerve (ASAN), together with bundles. Accordingly, the CS may vary its frequency and anatomical features. These variations can be identified through imaging technologies such as cone beam computed tomography (CBCT). The aim of this mini review is to present the current understanding of the CS, its prevalence and localization in order to decrease the potential surgical risk associated with this region. As revealed by the analysis of the international literature available, presence of CS is a crucial factor to consider in implantology and generally in oral surgery procedures in this area. In conclusions the use and analysis of CBCT imaging in the diagnosis stage is fundamental to preserve the most important anatomical structures which are present in the jaws.

Ultrasound imaging is gaining increasing relevance in facial aesthetic medicine due to its real-time, non-invasive, and radiation-free nature. The purpose of this scoping review was to explore the clinical applications of ultrasonography in aesthetic medicine. A comprehensive literature search was conducted using PubMed, Scopus, and Web of Science to identify clinical studies evaluating the use of ultrasonography in facial aesthetic medicine. The search strategy included the following terms: "aesthetic", "facial", "ultrasound". PRISMA Extension for Scoping Review guidelines were used. A total of 6 studies were included in this review. Ultrasonography has been used to guide injections in facial aesthetic procedures such as filler and botulinum injection and to assess the thickness of the masseter muscle to evaluate the efficacy of masseter muscle hypertrophy treatment. Ultrasonography enhances the safety of facial aesthetic procedures by guiding injections into the correct tissue layers and minimizing vascular risks. Priority should be given to the development of standardized protocols and an increase in randomized clinical trials.