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John Voss

Dr. John Voss

Department of Biochemistry & Molecular Medicine, Graduate Program in Biophysics,...

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John C. Voss completed his PhD study at the University of Minnesota Medical School. He then was a fellow at the Howard Hughes Medical and Jules Stein Eye institutes, UCLA, where he explored site-directed spin labeling approaches for engineered proteins. He is now a Professor at University of California, Davis where previously served as Chair of the Graduate Program in Biophysics. His awards include the Charles E. Culpeper Biomedical Initiative Award (1998), Basil O’Connor New Investigator Award, March of Dimes Foundation (2000), Scientist Development Award, American Heart Association (2000), Crafoord Visiting Professor award (2011), and the Wenner-Gren Foundation Visiting Scholar (2013). Dr. Voss specializes in using EPR spectroscopy to examine complex and dynamic ensembles, such as mis-folded proteins that underlie diseases of neurodegeneration. A general theme of the Voss research group is to employ biophysical approaches for elucidating the complexity of protein mis-folding with a goal of developing metal-free MRI contrast agents and CNS-active small molecule modulators to counter pathogenic protein conformations and oxidative stress.

Research Keywords & Expertise

Protein Aggregation
amyloid
ER stress
Protein misfolding
Inclusions

Fingerprints

28%
Spin-label
27%
Nitroxide
15%
amyloid
5%
Protein Aggregation
5%
Protein misfolding
5%
Catalytic antioxidant

Short Biography

John C. Voss completed his PhD study at the University of Minnesota Medical School. He then was a fellow at the Howard Hughes Medical and Jules Stein Eye institutes, UCLA, where he explored site-directed spin labeling approaches for engineered proteins. He is now a Professor at University of California, Davis where previously served as Chair of the Graduate Program in Biophysics. His awards include the Charles E. Culpeper Biomedical Initiative Award (1998), Basil O’Connor New Investigator Award, March of Dimes Foundation (2000), Scientist Development Award, American Heart Association (2000), Crafoord Visiting Professor award (2011), and the Wenner-Gren Foundation Visiting Scholar (2013). Dr. Voss specializes in using EPR spectroscopy to examine complex and dynamic ensembles, such as mis-folded proteins that underlie diseases of neurodegeneration. A general theme of the Voss research group is to employ biophysical approaches for elucidating the complexity of protein mis-folding with a goal of developing metal-free MRI contrast agents and CNS-active small molecule modulators to counter pathogenic protein conformations and oxidative stress.