SARS-CoV-2 is known to be a neurotrophic virus. However, the effect of this virus on the hearing system is still uncertain.We aimed to investigate the possible effect of COVID-19 on hearing.Thirty ... 背景：众所周知, SARS-CoV-2 是一种神经组织生长型病毒。然而, 这种病毒对听力系统的影响仍未确定。目的：我们旨在调查 COVID-19 对听力的可能影响。材料和方法：该研究包括30 名在过去 1 年中因某种原因进行纯音测听 (PTA)听力评估后感染 COVID-19 的医护人员。在30 名患者中, 对 15 名患者在其活性感染期进行了 PTA 和瞬态诱发耳声发射 (TEOAE) 测...

Aim: Newborn hearing screening is important for early detection of hearing loss in newborns. Gestational diabetes is a metabolic disease that can occur in pregnancy and cause complications such as those in the other diabetes mellitus patients. As uncomplicated gestational diabetes has not been described as a cause for prenatal complications in the literature, this study aimed to determine whether gestational diabetes is a risk factor for hearing impairment among newborns.Methods: This retrospective study included infants born between 2015 and 2017. The infants were divided into two groups: Control group consisted of 100 randomly selected children of healthy mothers. Study group consisted of 79 infants whose mothers had gestational diabetes mellitus. Exclusion criteria included other risk factors and 8 infants were excluded from the study due to risk factors other than gestational diabetes mellitus. The results of transient evoked otoacoustic emissions in infants of mothers with gestational diabetes were compared with those of infants of healthy mothers.Results: In this study, we compared transient evoked otoacoustic emission results of 71 infants of gestational diabetic mothers with 100 infants of healthy mothers. All the infants of healthy mothers, as well as the infants of mothers with gestational diabetes without risk factors, passed the transient evoked otoacoustic emission test. Conclusions: There was no difference detected in the hearing screening results between infants of mothers with gestational diabetes and infants of healthy mothers.

Introduction: This study was conducted to evaluate the effectiveness and safety of adjustable slings in the treatment of recurrent stress urinary incontinence (SUI) after mid-urethral sling (MUS) failure. Materials and Methods: A prospective study was performed among women with recurrent SUI at the Urogynecology Division of Istanbul School of Medicine between February 2010 and March 2015. All women were preoperatively evaluated with detailed urogynecologic evaluations, which included pelvic examination, Q-tip test, pad test, urodynamic studies and a compilation of the Kings Health Questionnaire (KHQ). Postoperative follow-up was performed at 1, 6 and 12 months and annually thereafter. Our primary outcome was objective cure and patient's satisfaction with treatment. Secondary outcomes included perioperative complications and adverse events. Results: Nineteen women were included in the study. The patients' mean age was 55.3 ± 6.9 years (range 43-66 years). The median follow-up time was 20.7 ± 14.0 months (range 6-55 months). The overall cure and improvement rates were 84.2 and 10.5%, respectively. In the satisfaction questionnaire, 15 (79%) patients responded that they were very satisfied and 3 (15.7%) were moderately satisfied. Sling tension re-adjustment was needed during follow-up in 1 patient (5.3%), 13 months after the initial surgery. The preoperative mean KHQ score was 545.9 ± 243.0 and changed to 237.0 ± 217.5 (p < 0.05). Postoperative complications were slight and easily manageable. Conclusions: Recurrent SUI is a challenging condition in urogynecology. The Regulation Mechanical External (Remeex) system has been found to be effective in the treatment of recurrent SUI after MUS failure with acceptable adverse effects. The Remeex system has the advantage of re-adjustment as a valuable option in the long-term management of patients.

Introduction The bone-anchored hearing implant system (BAHS) is an effective amplification system that transmits the sounds received by an external operating system to the inner ear by bypassing the middle ear placed in the temporal bone. Objective This study compares the results of patients who underwent bone-anchored hearing implant system (BAHS) surgery using two different surgical methods in terms of preoperative and postoperative complications, surgical time, audiological findings, and patient satisfaction. Methods The results of 22 patients who underwent BAHS were evaluated retrospectively from video records and audiological results, The Turkish Version of the Glasgow Benefit Inventory (GBI) questionnaire were evaluated. Two different surgical approaches were used for implantation: the linear incision technique (n = 9) and the punch technique (n = 13). Results Mean surgical durations were 9.67 ± 2.85 and 47.65 ± 6.13 minutes for Groups A and B, respectively, and these were significantly different (p < 0.001). There were no significant differences between the groups' speech recognition scores for a signal-to-noise ratio (SNR) of +5 (p = 0.173), SNR of 0 (p = 0.315), or SNR of -5 (p = 0.360) and results of the GBI scores. Conclusion The punch technique has a significant advantage due to a shorter surgery duration without increased surgical complications. Additionally, the punch technique showed no significant difference in hearing performance or satisfaction compared with linear incision.

No data have yet been published revealing the composition and the diversity of fungal communities (mycobiome) in the human middle ear cavity. The presented study investigated the mycobiome in the middle ear cavities of individuals with healthy middle ears and patients with otitis media with effusion. A total of 77 middle ear and four adenoid samples were collected from 47 individuals (35 children and 12 adults) in Group 1 and from 20 children in Group 2. The mycobiome profile was analyzed with nuclear ribosomal internal transcribed spacer 2 (ITS2) based metabarcoding using an Illumina MiSeq metagenomics kit. ITS2-based metabarcoding detected 14 different genera and 17 different species with a mean relative abundance of ≥1% in the samples analyzed. Mycobiome profile was similar between the adenoid tissue and the middle ear cavity, between Groups 1 and Group 2, and between children and adults. Fusarium, Stemphylium, Candida, and Cladosporium were the most abundant genera detected in all samples. The mean relative abundances of the genera Candida and Fusarium were remarkably higher in Group 2 compared to Group 1. The species Candida glaebosa, Candida cretensis, Aspergillus ruber, Penicillium desertorum, and Rhizopus arrhizus were significantly more abundant in patients with otitis media with effusion (OME), raising the possibility that they affect the pathogenesis of OME.