Block caving is a cost-effective mining method that enables the highly efficient mining of thick and large ore bodies. During ore extraction in block caving operations, the ore-drawing roadways require especially high safety standards. However, the complex in situ stress conditions and cyclic loading from caved ore significantly deteriorate the stability of the surrounding rock. This makes rock mass control particularly challenging, such that it is crucial to study an effective method for maintaining the long-term stability of the roadways. This research proposes a comprehensive approach combining laboratory rock mechanics testing, numerical simulation, and field engineering validation to design effective support strategies for disturbance-affected roadways. Laboratory tests provide accurate mechanical parameters for the rock mass, the numerical simulations allow for the comprehensive analysis of deformation–failure mechanisms under disturbance conditions, and field validation ensures the reliability and practical applicability of the proposed support method. This study focuses on a −285 m ore-drawing roadway in the western section of the Yanqianshan Iron Mine. The in situ stress distribution was characterized through rock mechanics testing and acoustic emission monitoring. The propagation mechanisms of ore-drawing disturbance waves within the rock mass were analyzed, and numerical simulations revealed the deformation patterns and failure modes under dynamic disturbance, upon which the support scheme was designed. The results demonstrate that the designed bolt–mesh–shotcrete support scheme can effectively control surrounding rock deformation within 5 mm and resists the deformation induced by cyclic disturbances. This study provides valuable technical support for stability management in block caving mines with similar conditions.