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Andrew Jones

Dr. Andrew Jones

Department of Biological and Medical Sciences, Faculty of Health and Life Scienc...

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Andrew Ken Jones, Oxford Brookes University, UK I completed my Biochemistry undergraduate degree at Imperial College London in 1996. I was then awarded a PhD at the University of Leeds in 2000, studying acetylcholinesterase and nicotinic acetylcholine receptors of the blood fluke, Schistosoma. In 2001, I carried on research of invertebrate cys-loop ligand-gated ion channels at the MRC Functional Genomics Unit, Oxford, until 2011. After a year of postdoctoral research at the Botnar Institute, Oxford, I became a Senior Lecturer in Molecular Biology and Genomics at Oxford Brookes University in 2012. My laboratory is interested in gene diversity and the resulting functional/pharmacological properties of ligand-gated ion channels using genome sequence analysis, molecular biology, and electrophysiology. In particular, I am focusing on cys-loop ligand-gated ion channels of insects. The cys-loop ligand-gated ion channel superfamily includes nicotinic acetylcholine receptors, GABA receptors, and glutamate-gated chloride channels, which play key roles in signalling and are also of interest as they are targets of pesticides. I am also interested in investigating changes (commonly mutations) in that give rise to pesticide resistance.

Research Keywords & Expertise

Ion Channels
Molecular Biology
Alternative splicing
heterologous expressio...
RNA editing

Fingerprints

35%
Ion Channels
20%
Alternative splicing
19%
RNA editing
9%
Insecticide targets
7%
heterologous expression
5%
gene diversity

Short Biography

Andrew Ken Jones, Oxford Brookes University, UK I completed my Biochemistry undergraduate degree at Imperial College London in 1996. I was then awarded a PhD at the University of Leeds in 2000, studying acetylcholinesterase and nicotinic acetylcholine receptors of the blood fluke, Schistosoma. In 2001, I carried on research of invertebrate cys-loop ligand-gated ion channels at the MRC Functional Genomics Unit, Oxford, until 2011. After a year of postdoctoral research at the Botnar Institute, Oxford, I became a Senior Lecturer in Molecular Biology and Genomics at Oxford Brookes University in 2012. My laboratory is interested in gene diversity and the resulting functional/pharmacological properties of ligand-gated ion channels using genome sequence analysis, molecular biology, and electrophysiology. In particular, I am focusing on cys-loop ligand-gated ion channels of insects. The cys-loop ligand-gated ion channel superfamily includes nicotinic acetylcholine receptors, GABA receptors, and glutamate-gated chloride channels, which play key roles in signalling and are also of interest as they are targets of pesticides. I am also interested in investigating changes (commonly mutations) in that give rise to pesticide resistance.