Elzbieta Budzisz

Prof. Elzbieta Budzisz

orcid

Research Focus & Metrics

Academic Career Length

35Years (1992-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2019 in Advances in Dermatology and Allergology
Verified
Journal Article
Open access
PDF file
MZMalwina Zasada
Malwina Zasada
EBElzbieta Budzisz
Elzbieta Budzisz
Vitamin A is the first vitamin approved by the Food and Drug Administration as an anti-wrinkle agent that changes appearance of the skin surface and has anti-aging effects. Vitamin A is in a group of fat-soluble substances and belongs to the category of retinoids. Apart from retinol, that group...

1 November 2009 in Coordination Chemistry Reviews
Verified
Journal Article
Closed access
MGMagdalena Grazul
Magdalena Grazul
EBElzbieta Budzisz
Elzbieta Budzisz

12 August 2021 in Molecules
Verified
Journal Article
Open access
PDF file
PMPAULINA ANTONINA MUCHA
PAULINA ANTONINA MUCHA
ASAnna Skoczynska
Anna Skoczynska
Magdalena MałeckaMagdalena Małecka
Magdalena Małecka
PHPaweł Hikisz
Paweł Hikisz
EBElzbieta Budzisz
Elzbieta Budzisz
Numerous plant compounds and their metal-ion complexes exert antioxidative, anti-inflammatory, anticancer, and other beneficial effects. This review highlights the different bioactivities of flavonoids, chromones, and coumarins and their metal-ions complexes due to different structural characteristics. In addition to insight into the most studied antioxidative properties of these compounds, the first part of the review provides a comprehensive overview of exogenous and endogenous sources of reactive oxygen and nitrogen species, oxidative stress-mediated damages of lipids and proteins, and on protective roles of antioxidant defense systems, including plant-derived antioxidants. Additionally, the review covers the anti-inflammatory and antimicrobial activities of flavonoids, chromones, coumarins and their metal-ion complexes which support its application in medicine, pharmacy, and cosmetology.


24 March 2020 in Molecules
Verified
Journal Article
Open access
PDF file
KKKinga Kasperkiewicz
Kinga Kasperkiewicz
Michał Błażej PonczekMichał Błażej Ponczek
Michał Błażej Ponczek
JOJacek Owczarek
Jacek Owczarek
PGPiotr Guga
Piotr Guga
EBElzbieta Budzisz
Elzbieta Budzisz
Many natural coumarins and their chemically synthesized analogs and derivatives exert diverse properties, such as anticancer, antioxidant, anti-inflammatory, or anticoagulant, with the latter being of the utmost importance. The widely used warfarin, acenocoumarol, and phenprocoumon exert anticoagulant properties by inhibiting the vitamin K epoxide reductase complex. In this interdisciplinary review, we present biochemical principles of the coagulation processes and possible methods for their tuning based on the use of coumarins. We also summarize chemical methods of synthesis of coumarins and discuss structures and properties of those that have been used for a long time, as well as newly synthesized compounds. Brief information on the clinical use of coumarins and other anticoagulant drugs is given, including the severe effects of overdosing and methods for reversing their action.

1 January 2017 in Advances in Dermatology and Allergology
Verified
Journal Article
Open access
PDF file
ASAnna Skoczyńska
Anna Skoczyńska
EBElzbieta Budzisz
Elzbieta Budzisz
ETEwa Trznadel-Grodzka
Ewa Trznadel-Grodzka
HRHelena Rotsztejn
Helena Rotsztejn
Discoloration are symptoms of skin aging. They are connected with presence of melanin and lipofuscin, whose excess and abnormal distribution in the skin cause dark spots to appear. Melanin is formed under the influence of tyrosinase during melanogenesis. Its content changes with age, which may be...