The COVID-19 outbreak is a global crisis that has placed small and medium enterprises (SMEs) under huge pressure to survive, requiring them to respond effectively to the crisis. SMEs have adopted various digital technologies to cope with this crisis. Using a data set from a survey with 518 Chinese SMEs, the study examines the relationship between SMEs’ digitalization and their public crisis responses. The empirical results show that digitalization has enabled SMEs to respond effectively to the public crisis by making use of their dynamic capabilities. In addition, digitalization can help improve SMEs’ performance. We propose a theoretical framework of digitalization and crisis responses for SMEs and present three avenues for future research.

In recent years, an emerging stream of research suggests that firms should use technological innovation and business model innovation harmoniously to maximize firm performance. In order to enrich the scholarly conversation on the fit between technological innovation and business model innovation, drawing insights from the dynamic capabilities perspective, this paper examines the fit between value proposition innovation and technological innovation (exploitative versus explorative) for the performance of startups in the digital environment. Based on on-site survey data of 285 digital startups in one of the world's largest digital economies, we find that explorative innovation strengthens the positive impact of value proposition innovation on the performance of startups, whereas exploitative innovation weakens this positive effect. Furthermore, these moderating effects are magnified in a highly uncertain demand environment. These findings inject fresh insights into existing scholarly conversation on the fit between technological innovation and business model innovation by offering a dynamic capabilities perspective and by extending it to an increasingly digital business environment.

Osteoporosis and sarcopenia are common age-related conditions characterized by the progressive loss of bone density and muscle mass, respectively. Their co-occurrence, often referred to as osteosarcopenia, presents significant challenges in elderly care due to increased fragility and functional impairment. Existing studies have identified shared pathological mechanisms between these conditions, including inflammation, hormonal imbalances, and metabolic dysregulation, but a comprehensive understanding of their molecular interplay remains incomplete. This study aims to deepen our understanding of the molecular interactions between sarcopenia and osteoporosis through an integrated omics approach, revealing potential therapeutic targets and biomarkers. Employing a combination of proteomics and transcriptomics analyses, this study analyzed bone and muscle tissue samples from patients diagnosed with osteoporosis and osteosarcopenia. Techniques included high-throughput sequencing and label-free proteomics, supported by advanced bioinformatics tools for data analysis and functional annotation of genes and proteins. The study found marked differences in gene and protein expressions between osteoporosis and osteosarcopenia tissues. Specifically, genes like PDIA5, TUBB1, and CYFIP2 in bone, along with MYH7 and NCAM1 in muscle, exhibited differential expression at both mRNA and protein levels. Pathway analyses revealed the significance of oxidative-reduction balance, cellular metabolism, and immune response in the progression of these conditions. Importantly, the study pinpointed osteoclast differentiation and NF-kappa B signaling pathways as critical in the molecular dynamics of osteosarcopenia, suggesting potential targets for therapy. This study utilized transcriptomics and proteomics to identify key genes and proteins impacting sarcopenia and osteoporosis, employing advanced network tools to delineate interaction networks and crucial signaling pathways. It highlighted genes like PDIA5 and TUBB1, consistently expressed in both analyses, involved in pathways such as osteoclast differentiation and cytokine interactions. These insights enhance understanding of the molecular interplay in bone and muscle degeneration with aging, suggesting directions for future research into therapeutic interventions and prevention strategies for age-related degenerative diseases.

This study advances managerial ties and firm performance research by examining the contingent value of resource bundling capabilities in the context of China's manufacturing industries. Using a sample of 290 manufacturing firms, we demonstrate that managerial ties and resource bundling capabilities can interactively impact firm performance. Specifically, business ties are positively related to, but political ties have an inverted U-shaped relationship with manufacturing firm performance. Further, business and political ties can interact to positively impact manufacturing firm performance. More importantly, improving resource bundling capabilities has a positive moderating effect on the relationship between managerial ties and manufacturing firm performance, whereas pioneering resource bundling capabilities has a negative moderating effect. Overall, we contribute to the literature by explicating different roles of business ties versus political ties played in creating value for manufacturing firms and extending the contingent view of managerial ties from a resource management perspective.