Introduction Stiffness is increased in vertebrae after kyphoplasty with bone cement is performed, which causes an increase in subsequent fractures in adjacent levels. This has led to increased interest in alternative filling materials such as bioactive calcium phosphate ceramics or silicon-based polymers. This study's objective is to compare the results between kyphoplasty with bone cement and with the VK100 silicone. Materials and methods This is a comparative, prospective study involving 64 patients, 23 treated using VK100 and 41 with PMMA. Clinical, radiological and functional results (Oswestry) and quality of life and (EQ-5D) were analysed and compared between both groups, focusing on differences in subsequent fractures in adjacent levels. Results There are no differences between the two treatments in terms of epidemiological factors (age and sex) or hospital management. A significant difference is observed in the gain of vertebral body height, with greater improvement in those treated with PMMA. There is also a higher fracture rate in the PMMA group, the difference is not significant. Finally, both treatments show similar outcomes in pain relief and quality of life. Conclusion Both VK100 Elastoplasty and PMMA Kyphoplasty are effective treatments for vertebral fractures. VK100 has a lower rate of complications and adjacent fractures. However, long-term results in terms of pain relief and quality of life are similar, making both treatments equally valid.

Stiffness is increased in vertebrae after kyphoplasty with bone cement is performed, which cause an increase in subsequent fractures in adjacent levels. This has led to increased interest in alternative filling materials such as bioactive calcium phosphate ceramics or silicon-based polymers. This study's objective is to compare the results between kyphoplasty with bone cement and with the VK100 silicone. This is a comparative, prospective study involving 64 patients 64 patients, 23 treated using VK100 and 41 with PMMA. Clinical, radiological and functional results (Oswestry) and quality of life and (EQ-5D).were analyzed and compared between both groups, focusing on differences in subsequent fractures in adjacent levels. There are no differences between the two treatments in terms of epidemiological factors (age and sex) or hospital management. A significant difference is observed in the gain of vertebral body height, with greater improvement in those treated with PMMA. There is also a higher fracture rate in the PMMA group, the difference is not significant. Finally, both treatments show similar outcomes in pain relief and quality of life. Both VK100 Elastoplasty and PMMA Kyphoplasty are effective treatments for vertebral fractures. VK100 has a lower rate of complications and adjacent fractures. However, long-term results in terms of pain relief and quality of life are similar, making both treatments equally valid.

Degenerative lumbar disorders are commonly treated with lumbar interbody fusion, but comparative evidence among ALIF, OLIF, and XLIF remains limited. This prospective multicenter observational cohort study compared perioperative outcomes, complications, and patient-reported outcomes (PROMs) after single- or multi-level ALIF, OLIF, or XLIF in 242 consecutive adults (108, 75, and 59, respectively) treated at Spanish centers. Age and surgical indications differed significantly across groups (p < 0.05), reflecting indication-based approach selection. Primary outcomes were intra- and postoperative complications through 6 months; secondary outcomes included operative time, blood loss, visual analog scale (VAS) pain scores, and the Oswestry Disability Index (ODI). XLIF had the shortest operative time (median, 63 min) and lowest blood loss. Overall intra- and postoperative complication rates were 3.3% and 7.8%, with no significant overall differences among techniques, although patterns differed: vascular injuries were associated with ALIF, cage subsidence was more frequent after XLIF, neurological deficits occurred with similar frequency in the XLIF and OLIF groups, and OLIF had the lowest intraoperative rate. All groups showed significant VAS and ODI improvements, with greater 6-month gains after ALIF and OLIF than after XLIF. These approaches are effective but have distinct risk–benefit profiles, supporting individualized selection.