Sung-Yun Chen

Ms. Sung-Yun Chen

orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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27 April 2021 in Public Health
Verified
Journal Article
Closed access
YTYi-Fan Tsai
Yi-Fan Tsai
SCSung-Yun Chen
Sung-Yun Chen
YYYung-Feng Yen
Yung-Feng Yen
THTsun-Cheng Huang
Tsun-Cheng Huang

26 January 2026 in Healthcare
Verified
Journal Article
Open access
PDF file
SLShih-Sen Lin
Shih-Sen Lin
SCSung-Yun Chen
Sung-Yun Chen
HTHsiao-Chi Tsai
Hsiao-Chi Tsai
SCShu-Fang Chang
Shu-Fang Chang
Background: Dynapenia refers to the age-related decline in muscle strength that occurs even when muscle mass is preserved. It has become an important issue in older adults because reduced strength is strongly linked to many negative health outcomes. When dynapenia occurs together with obesity—referred to as dynapenic obesity or dynapenic abdominal obesity—the risks, including mortality, falls, and the development of multiple chronic conditions, appear to increase even further. This umbrella review aimed to bring together and summarize existing systematic reviews and meta-analyses that examined how dynapenia and its obesity-related subtypes are associated with mortality, falls, and multimorbidity among community-dwelling older adults. Methods: Following PRISMA 2020 and JBI guidelines, six major databases and search engines (PubMed, Embase, Cochrane Library, Scopus, CINAHL, and Airiti Library) were searched from their inception to October 2025. Systematic reviews and meta-analyses involving adults aged 60 years and older and reporting quantitative results on the relationships between dynapenia-related conditions and adverse health outcomes were included. The methodological quality of each review was evaluated using AMSTAR 2, and the certainty of evidence was assessed with the GRADE approach. This umbrella review followed the PRIOR framework and was reported according to PRISMA 2020. The protocol for this review was registered in PROSPERO (ID: CRD 42023415232). Results: A total of four systematic reviews and meta-analyses were included, covering more than 73,000 community-dwelling older adults. The pooled data showed that dynapenic obesity significantly increased the risk of all-cause mortality, with hazard ratios ranging from 1.50 (95% CI 1.14–1.96) to 1.73 (95% CI 1.38–2.16). Dynapenic abdominal obesity was also strongly linked to falls, with pooled estimates ranging from HR = 1.82 (95% CI 1.04–3.17) to RR = 6.91 (95% CI 5.42–8.80). For multimorbidity, older adults with dynapenia had 1.38 times higher odds of having two or more chronic diseases than those without dynapenia (OR = 1.38, 95% CI 1.10–1.72). Based on the GRADE evaluation, the certainty of evidence was moderate for mortality and falls and low for multimorbidity. Conclusions: Overall, the findings indicate that dynapenia and its obesity-related forms meaningfully increase the risks of mortality, falls, and multimorbidity among community-dwelling older adults. Importantly, these results position dynapenia not merely as a musculoskeletal condition, but as a clinically relevant marker of aging-related vulnerability. This underscores the need for early screening of muscle strength alongside obesity-related indicators, as well as the development of integrated preventive strategies that combine strength-oriented interventions with obesity management in older populations.

15 July 2026 in Healthcare
Verified
Journal Article
Open access
PDF file
Shih-Sen LinShih-Sen Lin
Shih-Sen Lin
SCSung-Yun Chen
Sung-Yun Chen
SLShih-Chun Lin
Shih-Chun Lin
HTHsiao-Chi Tsai
Hsiao-Chi Tsai
YSYu-Chen Su
Yu-Chen Su
SCShu-Fang Chang
Shu-Fang Chang
Background: Dynapenic abdominal obesity (DAO), the coexistence of low muscle strength and abdominal obesity, may accelerate disability. However, its longitudinal association with disability remains unclear. In this study, we examined the relationship between DAO and disability in middle-aged and older adults. Methods: A systematic review and random-effects meta-analysis of prospective cohort studies was conducted to examine longitudinal associations following the PRISMA 2020 guidelines (PROSPERO: CRD42024609352). Comprehensive database searches were conducted in PubMed, Embase, MEDLINE (Ovid), CINAHL (EBSCOhost), and the Cochrane Library from database inception through 31 January 2025. To ensure that the review reflected the most recent evidence prior to manuscript submission, an updated search using the same search strategy and eligibility criteria was conducted on 31 May 2026. When multiple effect estimates were reported, the most fully adjusted estimates were selected. Because odds ratios (ORs) and hazard ratios (HRs) are different effect measures and are not directly comparable, they were analyzed separately. A random-effects model was used for quantitative synthesis. Results: Five cohort studies (n = 33,670; mean follow-up: 5.3 years) were included. Of these, four studies reported adjusted ORs and one reported an HR. DAO was associated with significantly higher odds of disability (pooled OR = 2.13, 95% CI: 1.74–2.60, I2 = 0%). Subgroup analyses demonstrated significant associations across predominant population types and age groups, with ORs ranging from 2.09 to 2.18. Conclusions: DAO is associated with increased odds of future disability across population types and age groups. These findings highlight the importance of early identification of DAO and suggest that interventions targeting muscle strength and abdominal obesity represent promising strategies for disability prevention; however, their effectiveness should be confirmed in future prospective intervention studies.