Biofuels, such as biodiesel, bioethanol, and biohydrogen produced from organic waste, constitute a sustainable alternative to non-renewable fuels and drive the energy transition. In this work, the inherent safety methodology was implemented to quantify and evaluate the intrinsic risks of obtaining hydrogen from African palm stems through direct gasification with Selexol. The methodology indicators were calculated with reference to databases, the literature, and safety data sheets, considering critical stages of the process. The total inherent safety index (I_SI) was 38, classifying the process as intrinsically unsafe, with the chemical component scoring 21 points, with hydrogen being the main chemical risk (8 points), along with hazards generated by chemical reactions. Likewise, high temperature and pressure conditions indicate the presence of potentially unsafe equipment such as reactors and heat exchangers, giving the process index 17 points. Based on the results, it is recommended to reduce raw material inventories and optimize operating conditions to reduce the potential for hazardous events and improve overall inherent safety.