Background: Various methods for preventing pressure injury have been developed across the globe, particularly in Saudi Arabia. Current available research has investigated the knowledge, attitudes, and practices regarding pressure injury prevention. However, no systematic review and meta-analysis have yet examined the associations among knowledge, attitudes, and practices regarding pressure injury prevention based on the perspectives of registered nurses. Objective: This study examines and summarizes the reported relationships among knowledge, attitudes, and practices regarding pressure injury prevention on the basis of the perceptions of registered nurses. Methods: The CINAHL, ProQuest, PubMed, ScienceDirect, and Web of Science databases were searched for quantitative evidence published in English between 2019 and 2025. The systematic review and meta-analysis adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (2021) guidelines. Results: Out of the 1986 records that were initially examined, a total of 10 quantitative, cross-sectional, and correlational studies were included in the final systematic review and meta-analysis. In the context of the meta-analysis, 10 studies were included for the association between knowledge and attitudes, whereas only 3 studies were available for the association between knowledge and practice, and similarly, only 3 studies addressed the association between attitudes and practice of pressure injury prevention. Collectively, 2457 registered nurses were involved in these studies, mostly working in intensive care units. The studies were conducted in various countries across Asia and the Middle East, mostly in Turkiye, within the last five years. The registered nurses in the 10 studies reported associations among knowledge, attitudes, and practices toward pressure injury prevention that ranged from insignificant to weak, indirect, and strong direct. Conclusions: Relationships among knowledge, attitudes, and practices toward pressure injury prevention are both positive and negative from the global perspective and are shaped by various confounding and mediating factors, including socio-demographic, nursing-related, and hospital-related factors. Improving the knowledge base of registered nurses and promoting a favorable attitude toward pressure ulcer prevention would provide healthcare organizations with the potential to enhance the already commendable levels of practice and prevention noted in this review.

OBJECTIVE: Pressure injuries (PIs) remain a significant challenge in healthcare, causing patient discomfort, prolonging hospital stays, and imposing substantial financial burdens on healthcare systems. Despite advancements in prevention strategies, determining the most cost-effective interventions remains paramount for healthcare providers and policymakers. The study authors aimed to assess the cost-effectiveness of various PI prevention strategies within a quasi-experimental design framework. METHODS: A quasi-experimental study with 2 arms was conducted between September 2022 and February 2023 in a hospital in Saudi Arabia: the routine care for the PI group, group 1, and the PI prevention bundle group, group 2. Data on PI incidence, severity, and associated costs were collected to compare outcomes between group 1 and group 2. RESULTS: A total of 368 patients were enrolled in the study: 218 patients in group 1 and 150 in group 2. Mortality was higher in the routine care group. The mean PI-free day in the prevention bundle group was 298.8 days compared with 19.7 days in the routine care group. Overall, the mean total cost for the bundle care group was ~$9600 lower than that of the routine care group. CONCLUSIONS: This quasi-experimental study confirmed that PI prevention is cost-effective. Hospitals should invest in interdisciplinary teams and prevention bundles to improve patient outcomes and resource utilization.

Background: and objective: Globally, breast cancer (BC) raises global health concerns, being the most common cancer. Women with BC experience a significant increase in perception of stress. Therefore, this study aims to evaluate the stress levels and associated sociodemographic and clinical factors among BC women in Saudi Arabia. Methods: A cross-sectional study was conducted between January and May 2025. Women diagnosed with BC, who were at least 18 years old, were recruited conveniently from outpatient and inpatient departments in King Fahad Specialist Hospital, Dammam, Saudi Arabia. Data were collected in the Arabic language through self-reported questionnaires, including sociodemographic/clinical characteristics and the Cohen’s Perceived Stress Scale. The data were analyzed using the Statistical Package for the Social Sciences (SPSS) version 27. Results: A total of 200 participants were included in the study. The mean stress perception score was 26.52 ± 7.34. A high proportion (71.5%) of the sample reported elevated stress. A significant association was observed between age and stress levels. Most women aged 20–40 and 41–60 reported high stress, compared to women in the 61–80 age group (p = 0.003). Among all predictors, age was the only variable significantly associated with stress scores. Increasing age was associated with lower stress levels (B = −0.179, p = 0.013), indicating that younger participants tended to report higher stress. This corresponds to an adjusted decrease of approximately 1.8 points in the PSS-10 score per 10-year increase in age. Although participants with Stage IV cancer showed higher stress scores compared to those with Stage I cancer, this association approached but did not reach statistical significance (p = 0.054). Conclusions: This study highlights the substantial psychological burden experienced by women living with BC in Saudi Arabia. The majority of participants reported high levels of perceived stress. Younger women were particularly vulnerable to elevated stress. These findings highlight the need for targeted psychosocial support within oncology care to improve emotional well-being and quality of life.

Nursing students faced learning losses during the COVID-19 pandemic due to the transition to virtual classes, inadequate communication, and reliance on virtual clinical training as a prerequisite for clinical practice. This study aimed to investigate the extent of learning loss experienced by nursing students and examine the impact of simulation-based learning (SBL) on mitigating this learning loss and on students’ confidence, satisfaction, and performance before and after the SBL program. This quasi-experimental study used a within- and between-subjects design. Data were collected from January 2022 to May 2023 from 177 nursing students before and after the SBL program. The Learning Loss scale and Simulation Training Evaluation Questionnaire were used. Substantial learning losses were observed in nurses’ knowledge, professional attitude, and skills before the intervention. The intervention group had significantly higher knowledge, professional attitude, and professional skills than the control group. The intervention significantly improved nursing students’ confidence, expectations/satisfaction, and performance. The regression model revealed that age and weeks in internship were significant predictors of learning loss. Prior distance education experience did not show any significant association with learning loss. Thus, SBL is useful in crisis situations; it enhances nursing students’ knowledge, professional attitudes, and professional skills. Course designers should consider integrating SBL into nursing curricula as an innovative teaching strategy to compensate for possible learning losses. This approach will help prepare graduates to enter the workforce with the ability to quickly adapt and practice confidently in clinical settings to ensure patient safety.

Medical device‐related pressure injuries (MDRPIs) are a patient safety concern in acute and critical care settings. Registered nurses must implement preventive strategies, yet gaps remain in their knowledge, attitudes, and clinical practices related to MDRPI prevention. This study aimed to evaluate the effectiveness of a structured educational intervention in improving registered nurses' knowledge, attitudes, and practices related to MDRPI prevention. A quasi‐experimental pre–post intervention study was conducted in a tertiary care hospital in Saudi Arabia, with 311 registered nurses participating. Data were collected using a questionnaire assessing knowledge, attitudes, and practices related to MDRPI prevention. Participants received a one‐day structured educational program based on the knowledge, attitude, practice (KAP) framework and the evidence‐based SKINCARE bundle. The educational intervention resulted in significant improvements. Mean scores increased from 14.17 (SD = 2.38) pre‐intervention to 16.25 (SD = 1.97) post‐intervention ( t = −11.81, p < 0.001). The intervention demonstrated a moderate‐to‐large effect size (Cohen's d = 0.67), indicating meaningful improvement in nurses' preventive competencies. Structured educational programs can enhance registered nurses' knowledge and practices in MDRPI prevention. Integrating evidence‐based training programs into routine hospital education may strengthen pressure injury prevention guidelines and improve patient safety outcomes.

Global demand for health economics/pharmacoeconomics (HE/PE) has significantly increased, leading to a greater need for competent and skilled healthcare professionals in this field. However, the current literature indicates a lack of research regarding HE/PE among healthcare professionals, including those in the Kingdom of Saudi Arabia (KSA), particularly among registered nurses. Hence, this study assessed registered nurses’ levels of awareness and knowledge of HE/PE and their sociodemographic and HE/PE-related predictors. A descriptive–correlational, cross-sectional design was used. The study was conducted on a convenience sample of 324 registered nurses working at the three hospitals within King Saud University Medical City, Riyadh, KSA. Data were collected from May 2025 to June 2025, and analyzed using SPSS v.30. Binary logistic regression analyses were conducted for HE/PE awareness, and multiple linear regression analyses were performed for knowledge about HE/PE. The significance level was established at p <0.05. Registered nurses demonstrated an overall low level of knowledge (2.39/5), while showing a good level awareness about HE/PE across four awareness items (52.8% to 84.6%) but suboptimal for the remaining two items (38.6% and 38.9%). Several sociodemographic and HE/PE-related factors were identified as significant predictors of the registered nurses’ awareness and knowledge regarding HE/PE. Notably, four out of the six awareness items: “have heard about HE/PE” (p =0.040), “read articles related to HE/PE regularly” (p <0.001), “participate in HE/PE decisions at work” (p <0.042), and “implement HE/PE techniques to make decisions” (p <0.001) were revealed as significant predictors of registered nurses’ knowledge about HE/PE. The findings indicate that the knowledge level regarding HE/PE among registered nurses was low; nevertheless, their awareness was acceptable. It is crucial to develop and implement targeted educational strategies and interventions aimed at enhancing both awareness and knowledge about HE/PE among registered nurses in the KSA, while meticulously considering pertinent sociodemographic and HE/PE-related factors.