Giuseppe Iacomino, PhD, is Senior Staff Scientist at the Institute of Food Sciences of the National Research Council of Italy (CNR). He graduated cum laude in Biological Sciences from the University of Naples in 1989, earned a PhD in Biochemistry, and specialized in Biochemistry and Clinical Chemistry. His scientific training was carried out in the laboratories of Prof. Vincenzo Zappia (Biochemistry) and Prof. Antonino Cascino (Molecular Biology) at the University of Naples. His research covers Biochemistry, Molecular and Cell Biology, Nutritional Sciences, Cancer Biology, and Cancer Prevention, focusing on molecular mechanisms linking diet, gene regulation, and human health. His studies address chemoprevention, diet-related diseases, epigenomics, chromatin dynamics, transcriptional regulation, cell-cycle control, apoptosis, and nutrient-mediated epigenetic modulation. A major research interest is the role of polyamines in nuclear organization. He contributed to the characterization of Nuclear Aggregates of Polyamines (NAPs), supramolecular structures interacting with genomic DNA and influencing its conformation, protection, and packaging. His work investigates food valorization through bioaccessibility, biotransformation, and intestinal transport of bioactive compounds using in vitro digestion models and human intestinal cells. More recently, he has focused on microRNA signatures in obesity, metabolic, inflammatory, and rare diseases, contributing to disease mechanism identi