The research interests of the Prof Domenico Tricarico focus on molecular target characterization through the pharmacology of ion channels involved in neuromuscular, metabolic acquired and genetic diseases, and in proliferative disturbances; toxicological and pharmacological investigation in vitro and in vivo, risk/benefit/cost analyses of experimental drugs and post-marketing surveillance through toxicological, pharmacovigilance, and pharmacoeconomic investigations; physiology/pharmacology/toxicology focusing on advanced ion channel biophysics, molecular biology, and pharmacology; skeletal muscle pathophysiology, pharmacology, and toxicology focusing on disorders affecting the neuromuscular apparatus, ion channel-related diseases, and insulin/glucose dysmetabolisms; and drug development focusing on the principles of drug development and the evaluation of experimental protocols in various therapeutic areaa.
Research Keywords & Expertise
Bone
Cell Cycle
Trp Channels
AKT
Ca2+-activated K+(BK) ...
Calcium ions
Cell volume
KATP and Kir channels
Fingerprints
17%
Bone
10%
Cell Cycle
8%
AKT
8%
Ca2+-activated K+(BK) channel
5%
Cell volume
5%
KATP and Kir channels
5%
Calcium ions
Short Biography
The research interests of the Prof Domenico Tricarico focus on molecular target characterization through the pharmacology of ion channels involved in neuromuscular, metabolic acquired and genetic diseases, and in proliferative disturbances; toxicological and pharmacological investigation in vitro and in vivo, risk/benefit/cost analyses of experimental drugs and post-marketing surveillance through toxicological, pharmacovigilance, and pharmacoeconomic investigations; physiology/pharmacology/toxicology focusing on advanced ion channel biophysics, molecular biology, and pharmacology; skeletal muscle pathophysiology, pharmacology, and toxicology focusing on disorders affecting the neuromuscular apparatus, ion channel-related diseases, and insulin/glucose dysmetabolisms; and drug development focusing on the principles of drug development and the evaluation of experimental protocols in various therapeutic areaa.