Background/Objectives: Penile urethral stricture is a therapeutically challenging condition that significantly impacts quality of life and is often managed initially with urethral dilation or internal urethrotomy. However, both techniques are associated with high recurrence rates, limited long-term efficacy, and potential adverse effects, particularly in the penile urethra. Urethroplasty remains the gold standard but is invasive and not suitable for all patients. Optilume, a paclitaxel-coated balloon, combines mechanical dilation with localized drug delivery to reduce recurrence rates and the need for re-intervention. This study evaluated its effectiveness in patients with penile urethral strictures. Methods: A retrospective, multicenter study was conducted at two German clinics. Eight male patients (mean age 59) with symptomatic penile urethral strictures underwent Optilume treatment. Symptom severity was assessed using the International Prostate Symptom Score (IPSS) and quality of life (QoL) scores before and after treatment. The primary endpoint was symptom improvement, while the secondary endpoint was the need for reintervention. Patients were followed for a median of 16.5 months. Statistical analyses included Wilcoxon signed-rank and Mann–Whitney U tests. Results: The median IPSS improved from 25.5 to 5.0 and QoL scores from 4.5 to 1.0 after treatment (p < 0.01 for both). No patients required reintervention during follow-up. The subgroup analysis showed slightly better outcomes in patients without prior interventions, although differences were not statistically significant. The stricture length did not correlate with treatment response. Conclusions: Optilume significantly reduces urinary symptoms and improves QoL in penile urethral strictures, and the absence of re-interventions during follow-up underscores its durable mid-term success. It offers a minimally invasive alternative to urethroplasty, particularly for patients seeking symptom relief with a shorter recovery time and no hospital stay or general anesthesia. These preliminary findings suggest that Optilume may be a promising minimally invasive option for selected patients. Larger, controlled studies are warranted to validate these results and refine patient selection criteria.
Background: Video content has become an increasingly valuable tool in medical education, particularly for teaching hands-on skills like sonography and clinical examination. This study evaluates the satisfaction and content of sonography and clinical examination videos on the AMBOSS platform, a prominent medical education resource in Germany. Objective: The goal of this study was to compare how effective and well-received sonography and clinical examination videos are on the AMBOSS platform. The study looked at aspects such as the medical and technical quality of the videos, their usefulness for learning, and overall user satisfaction. Methods: Eighteen instructional videos were chosen and made accessible on the AMBOSS platform, grouped into sonography (n = 9) and clinical examination (n = 9) categories. Users were asked to voluntarily and anonymously fill out a questionnaire evaluating the videos. Over 49.5 months, data from 1,643,274 video views and 936 completed questionnaires were gathered. Results: Clinical examination videos were watched significantly more often than sonography videos (86 vs. 14%). Both video types were highly rated in terms of medical and technical quality. However, sonography videos were judged superior in technical quality and clarity, whereas clinical examination videos were preferred for their medical quality and practical application. Feedback from users indicated a desire for more detailed annotations and clearer explanations. Conclusion: The findings underline the crucial role of video resources in medical education, particularly in teaching practical skills. To improve educational outcomes, it is important to tailor content to the specific needs of medical students and professionals, incorporate user feedback, and take advantage of technological advancements.
1 January 2026 in Central European Journal of Urology
The Central European Journal of Urology is an open access quarterly-issued journal, which provides a forum for the presentation of original clinical, experimental and other research studies...