Background/Objectives: The objective of this study was to assess the diagnostic accuracy of the Triglyceride-Glucose (TyG) index for screening gestational diabetes mellitus (GDM) at 24–28 weeks of gestation, to determine its optimal diagnostic threshold, and to compare its predictive performance with conventional lipid ratios (LDL/HDL, TG/HDL, and TC/HDL). Materials and Methods: We retrospectively analyzed 440 pregnant women with singleton pregnancies who underwent a 75 g oral glucose tolerance test (OGTT) between January and July 2025. The TyG index and lipid ratios were calculated, and their associations with GDM were evaluated. Subgroup analyses were conducted to assess the efficacy of the TyG index in predicting GDM, using logistic regression to estimate odds ratios (ORs) with 95% confidence intervals (CIs), and receiver operating characteristic (ROC) curve analysis along with restricted cubic spline modeling to evaluate diagnostic performance and determine the optimal cutoff value. Results: The overall prevalence of GDM, as defined by the IADPSG (International Association of the Diabetes and Pregnancy Study Groups) criteria, was 22.7%. The median TyG index was significantly higher in the GDM group compared with the non-GDM group (9.1 vs. 8.9, p = 0.001). The TyG index was a significant predictor of GDM (p < 0.05), with each one-unit increase associated with significantly higher odds of GDM (OR = 12.29), after adjusting for covariates. ROC analysis demonstrated an AUC of 0.716 (95% CI: 0.627–0.793, p < 0.001) for the TyG index, and the optimal cut-off value was identified as 9.35, yielding a sensitivity of 38.5% and a specificity of 96.5% and a negative predictive value of 83.7%. Subgroup analyses indicated that the TyG index had limited discriminative ability for predicting GDM in both the post-load and insulin-requiring groups. Among conventional lipid ratios, TG/HDL demonstrated the highest predictive performance (AUC = 0.587), while LDL/HDL (AUC = 0.483) and TC/HDL (AUC = 0.509) demonstrated low predictive accuracy. Compared with conventional lipid ratios, the TyG index demonstrated superior predictive performance. Conclusions: A higher TyG index was positively associated with the development of GDM and showed better predictive ability than conventional lipid ratios. However, its low sensitivity limits its use as a standalone diagnostic tool, suggesting it may be most useful when combined with other clinical parameters.

Background and Objectives: Vaginal uterine manipulators facilitate laparoscopic hysterectomy but are limited by cost and anatomical constraints. The Boztosun method offers a cost-effective intra-abdominal alternative. This study evaluated the clinical performance and safety of this technique. Materials and Methods: This single-center, retrospective descriptive study analyzed 40 patients who underwent laparoscopic hysterectomy using the Boztosun method at Akdeniz University Hospital between October 2021 and June 2022. Clinical characteristics and perioperative outcomes were assessed. Results: The mean operative time was 78.5 ± 20.6 min, and the mean colpotomy time was 8.05 ± 3.57 min. Conversion to laparotomy occurred in 3 patients (7.5%), primarily due to extensive adhesions or large uterine size. No intraoperative complications, organ injuries, or blood transfusions were recorded. All patients were discharged within two days. Patients with prior abdominal surgery had significantly longer operative and colpotomy times (p < 0.05). Conclusions: The Boztosun method is a safe, efficient, and low-cost alternative to vaginal manipulators in laparoscopic hysterectomy. It may be particularly useful in resource-limited settings or when vaginal manipulation is not feasible.

Objective: This study aimed to evaluate the prognostic significance of systemic immune-inflammatory indices, including the systemic immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR), in patients with epithelial ovarian cancer (EOC).Material and Methods: A retrospective analysis was conducted in patients with EOC diagnosed at Akdeniz University Hospital between 2005 and 2019. Patients with hematologic malignancies, autoimmune disorders, chronic inflammatory diseases, or a history of other cancers were excluded. Preoperative and postoperative hematologic parameters were recorded. The prognostic value of immune-inflammatory indices was assessed using nn-Meier survival analysis, Cox regression, and receiver operating characteristic (ROC) analysis.Results: A total of 264 EOC patients were included. Postoperative SII and NLR values were significantly higher than the preoperative levels (p

The relationships among job satisfaction, psychological hardiness, and mental workload among healthcare personnel working in gynecology and obstetrics clinics remain insufficiently understood. To examine the proposed mediating role of psychological hardiness in the relationship between job satisfaction and mental workload among the healthcare personnel working in gynecology and obstetrics clinics. This cross-sectional study included 183 healthcare professionals working in gynecology and obstetrics clinics at a training and research hospital in eastern Turkey. Data were collected using a sociodemographic form, the Minnesota Satisfaction Questionnaire, the Mental Workload Scale, and the Psychological Hardiness Scale. The proposed mediation model was examined using observed-variable path analysis with maximum likelihood estimation and 5,000 bootstrap resamples. Job satisfaction was positively associated with psychological hardiness (β = 0.439, p < 0.001) and negatively associated with mental workload after accounting for psychological hardiness (β = −0.276, p < 0.001). Psychological hardiness was not significantly associated with mental workload after accounting for job satisfaction (β = 0.094, p = 0.240). The indirect effect was not statistically significant (B = 0.025, bias-corrected bootstrap 95% CI: −0.019 to 0.076, p = 0.228). The model explained 19.3% of the variance in psychological hardiness and 6.2% of the variance in mental workload. Higher job satisfaction was associated with lower mental workload and greater psychological hardiness. The findings did not support the proposed mediating role of psychological hardiness. Longitudinal studies are needed to clarify the temporal relationships among these variables.