Background: The aim of this study was to determine the recurrence rate of patients who did not have interval cholecystectomy after treatment with percutaneous cholecystostomy and to investigate the factors that may affect the recurrence. Methods: Patients who did not undergo interval cholecystectomy after percutaneous cholecystostomy treatment between 2015 and 2021 were retrospectively screened for recurrence. Results: 36.3% of the patients had recurrence. Recurrence was found more frequently in patients with fever symptoms at the time of admission to the emergency department (p = 0.003). Recurrence was found to be more frequent in those who had a previous cholecystitis attack (p = 0.016). It was determined that patients with high lipase and procalcitonin levels had statistically more frequent attacks (p = 0.043, p = 0.003). It was observed that the duration of catheter insertion was longer in patients who had relapses (p = 0.019). The cut-off value for lipase was calculated as 15.5, and the cut-off value for procalcitonin as 0.955, in order to identify patients at high risk for recurrence. In the multivariate analysis for the development of recurrence, presence of fever, a history of previous cholecystitis attack, lipase value higher than 15.5 and procalcitonin value higher than 0.955 were found to be risk factors. Conclusions: Percutaneous cholecystostomy is an effective treatment method in acute cholecystitis. Insertion of the catheter within the first 24 h may reduce the recurrence rate. Recurrence is more common in the first 3 months following removal of the cholecystostomy catheter. Having a previous history of cholecystitis attack, fever symptom at the time of admission, elevated lipase and procalcitonin are risk factors for recurrence.
The aim of this study was to determine the impact of preoperative prognostic nutritional index (PNI) value and skeletal muscle area (SMA) on short-term outcomes of patients with gastric cancer.A to...
24 June 2022 in Turkish Journal of Colorectal Disease
Aim: Weight loss and malnutrition are frequently observed in patients with gastric cancer. Therefore, nutrition is important, especially in patients with gastric cancer. In this study, we aimed to identify the effect of preoperative nutritional support on postoperative morbidity and mortality in patients with gastric cancer. Material and Method: A total of 110 patients underwent gastrectomy due to gastric cancer between December 2015 and December 2019 were retrospectively analyzed. It was determined whether the patients were given preoperative and postoperative nutritional support. Clinicopathological features and short-term results were compared. Results: Overall morbidity was 29.1% (n=32) in patients who underwent gastrectomy. It was observed that the rate of major complications increased statistically with increasing age (p<0.001). Comorbidity was also found to be a risk factor for major complications (OR 3.917, 95% CI 1.423-10.781; p=0.006). The incidence of complications increases especially in patients with a diagnosis of diabetes (OR 3.743, 95% CI 1.201-11.666; p=0.040). While anastomotic leak developed in 6.7% (n=2) of the patients who were taken preoperative nutrition, anastomotic leak developed in 10% (n=8) of the patients who were not taken nutritional support (p=0.588). Likewise, the relationship between the postoperative length of stay, postoperative complications and mortality of patients receiving preoperative nutritional support could not been proven. Conclusion: The present study reveals that preoperative nutrition in patients with gastric cancer was not associated with improved morbidity and mortality rates. Large, multicenter prospective studies focusing on preoperative nutritional support are needed to uncover the exact relation of preoperative nutrition and morbidity-mortality rates in patients with gastric cancer.
27 March 2023 in Turkish Journal of Colorectal Disease