Sebastian Guzman Alfaro

Dr. Sebastian Guzman Alfaro

orcid

Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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26 December 2025 in Diagnostics
Verified
Journal Article
Open access
PDF file
SASebastian Guzman Alfaro
Sebastian Guzman Alfaro
KVKaren E. Villagrana-Bañuelos
Karen E. Villagrana-Bañuelos
MSManuel A. Soto-Murillo
Manuel A. Soto-Murillo
Carlos Eric Galván-TejadaCarlos Eric Galván-Tejada
Carlos Eric Galván-Tejada
ABAntonio Baltazar-Raigosa
Antonio Baltazar-Raigosa
ACAndrea Acuña Correa
Andrea Acuña Correa
Background/Objectives: Cardiovascular diseases are the leading cause of mortality worldwide according to the World Health Organization (WHO), highlighting the need for accessible tools for early detection. Automated classification systems based on signal processing and machine learning offer a non-invasive alternative to support clinical diagnosis. Methods: This study implements and evaluates machine learning models for distinguishing normal and abnormal heart sounds using a hybrid feature extraction approach. Recordings labeled as normal, murmur, and extrasystolic were obtained from the PASCAL dataset and subsequently binarized into two classes. Multiple numerical datasets were generated through statistical features derived from Mel-Frequency Cepstral Coefficients (MFCCs) and Daubechies wavelet analysis. Each dataset was standardized and used to train four classifiers: support vector machines, logistic regression, random forests, and decision trees. Results: Model performance was assessed using accuracy, precision, recall, specificity, F1-score, and area under curve. All classifiers achieved notable results; however, the support vector machine model trained with 26 MFCCs and Daubechies-4 wavelet coefficients obtained the best performance. Conclusions: These findings demonstrate that the proposed hybrid MFCC–Wavelet framework provides competitive diagnostic accuracy and represents a lightweight, interpretable, and computationally efficient solution for computer-aided auscultation and early cardiovascular screening.

1 May 2026 in Bioengineering
Verified
Journal Article
Open access
PDF file
Misael Zambrano-de la TorreMisael Zambrano-de la Torre
Misael Zambrano-de la Torre
SASebastian Guzman Alfaro
Sebastian Guzman Alfaro
ACAndrea Acuña Correa
Andrea Acuña Correa
MSManuel A. Soto-Murillo
Manuel A. Soto-Murillo
Maximiliano Guzman FernandezMaximiliano Guzman Fernandez
Maximiliano Guzman Fernandez
ECErik O. Cuevas-Rodriguez
Erik O. Cuevas-Rodriguez
Recent advances in edge computing and Tiny Machine Learning (TinyML) have enabled the deployment of artificial intelligence models directly on microcontrollers with extremely limited computational and memory resources. In this context, this work presents the design, implementation, and validation of a real-time cardiac arrhythmia classification system based on a quantized one-dimensional convolutional neural network (1D-CNN), deployed on an 8-bit Arduino UNO microcontroller. The proposed system integrates end-to-end processing, including ECG signal acquisition using a low-cost AD8232 analog front-end, signal preprocessing, heartbeat segmentation, classification, and real-time visualization on an OLED display. The model was trained and evaluated using the MIT-BIH Arrhythmia Database, considering a reduced three-class problem (Normal, Ventricular, and Supraventricular) to meet the constraints of ultra-low-cost hardware deployment. Under benchmark conditions, the quantized model achieved an accuracy of 97.6%, with a memory footprint below 24 KB and an average inference time of 200 ms per heartbeat, enabling real-time operation on a resource-constrained microcontroller. Real-time experiments were conducted using signals acquired from healthy volunteers to validate system functionality, although no annotated ground truth was available for these recordings, and therefore no diagnostic performance was derived from them. The results demonstrate the feasibility of deploying lightweight deep learning models on ultra-constrained embedded systems using the TinyML paradigm, implemented using TensorFlow 2.15 and TensorFlow Lite. This work should be interpreted as a proof-of-concept platform that highlights the trade-off between classification performance and hardware limitations, providing a foundation for future development of low-cost cardiac monitoring technologies in resource-limited environments.

5 March 2026 in Applied Sciences
Verified
Journal Article
Open access
PDF file
Misael Zambrano-de la TorreMisael Zambrano-de la Torre
Misael Zambrano-de la Torre
SASebastian Guzman Alfaro
Sebastian Guzman Alfaro
Maximiliano Guzman FernandezMaximiliano Guzman Fernandez
Maximiliano Guzman Fernandez
RORicardo Robles Ortiz
Ricardo Robles Ortiz
CSCarlos Humberto Espino Salinas
Carlos Humberto Espino Salinas
ARAna Gabriela Sánchez Reyna
Ana Gabriela Sánchez Reyna
Environmental monitoring across extensive regions is often constrained by the high costs of conventional laboratory analysis. This study proposes a methodology for electrophysiological characterization of Aloe vera as a potential biological dosimeter for low-cost environmental sensing. Using an ATMega328P-based acquisition system with high-input-impedance signal conditioning, we recorded plant biopotentials under controlled abiotic stressors. Signal variations were evaluated as a function of leaf morphology, electrode placement, and environmental variables, including light intensity, soil moisture, water saturation, and pH. The statistical validation included Jaccard similarity coefficients for repeatability and Kruskal–Wallis tests for group comparisons. The measurements showed highly repeatable baseline behavior (Jaccard similarity in the range 0.95–0.99) and significant differences across stress conditions, particularly under changes in light intensity. These findings support the feasibility of using Aloe vera electrophysiological signals as a robust and low-cost basis for developing plant-based biosensing approaches in environmental monitoring applications.

5 March 2025
Verified
Book Chapter
Closed access
PDF file
SASebastian Guzman Alfaro
Sebastian Guzman Alfaro
JRJosé I. Ríos-Ríos
José I. Ríos-Ríos
JPJose Maria Padilla
Jose Maria Padilla
Carlos Eric Galván-TejadaCarlos Eric Galván-Tejada
Carlos Eric Galván-Tejada
AFAngeles O. Félix-Castañeda
Angeles O. Félix-Castañeda
ACAndrea Acuña Correa
Andrea Acuña Correa

30 April 2025
Verified
Book Chapter
Closed access
PDF file
JRJosé I. Ríos-Ríos
José I. Ríos-Ríos
AMAntonio Martinez-Torteya
Antonio Martinez-Torteya
MSManuel A. Soto-Murillo
Manuel A. Soto-Murillo
JPJose Maria Padilla
Jose Maria Padilla
Carlos Eric Galván-TejadaCarlos Eric Galván-Tejada
Carlos Eric Galván-Tejada
Luis Carlos RevelesLuis Carlos Reveles
Luis Carlos Reveles