Background/Objectives: Atrial fibrillation (AF) is a prevalent cardiac arrhythmia associated with significant morbidity, including stroke, heart failure, and increased mortality, necessitating oral anticoagulant (OAC) therapy to reduce thromboembolic risk. However, OACs, including warfarin and non-vitamin K antagonist oral anticoagulants (NOACs), increase the risk of gastrointestinal (GI) bleeding, a serious complication requiring precise risk stratification in the emergency department (ED). Methods: This retrospective cohort study was conducted in the Emergency Department of Balikesir University Hospital in Turkey between 2019 and 2023 and evaluates systemic inflammatory markers as predictors of GI bleeding in AF patients receiving OACs. A total of 155 patients were divided into case (GI bleeding) and control (no GI bleeding) groups, comparing demographics, comorbidities, CHA₂DS₂-VASc and HAS-BLED scores, and inflammatory indices (uric acid/albumin ratio, neutrophil-to-lymphocyte ratio [NLR], platelet-to-lymphocyte ratio [PLR], systemic immune inflammation index [SII]). Results: For patients receiving NOACs, the case group exhibited significantly higher uric acid/albumin ratio, NLR, PLR, and SII (p < 0.05). For patients receiving warfarin, only the uric acid/albumin ratio was significantly elevated (p < 0.001). Hypolipidemia and elevated uric acid were associated with bleeding risk in patients receiving NOACs, while hypoalbuminemia and elevated urea predicted bleeding in patients receiving warfarin. HAS-BLED scores were significantly higher in bleeding groups, unlike CHA₂DS₂-VASc scores. Conclusions: These findings suggest that inflammatory indices, particularly in patients taking NOACs, are associated with GI bleeding risk stratification. Integrating these biomarkers into clinical practice could optimize personalized anticoagulation strategies, reducing morbidity and mortality in AF patients.

Background/Objectives: One of the most prevalent reasons for attending the emergency department (ED) is chest pain. There are many causes of its etiology. Recent studies indicate that coronary slow flow should be considered not only an angiographic phenomenon but also a clinical syndrome. In our study, we aimed to identify laboratory parameters indicative of coronary slow flow. Methods: Patients who presented to the Emergency Department of Balikesir University Hospital with chest pain and underwent coronary angiography between 2019 and 2023 were evaluated. A group of 107 patients with primary coronary slow flow was included as the patient group, while 108 patients without any pathology were included as the control group. Demographic, laboratory, clinical, and angiographic parameters were compared between the two groups to determine the predictors of coronary slow flow. Results: In our study, RCA dominance was detected in the control group, while Cx dominance was detected in our patient group (p < 0.001). CRP and the CRP/albumin ratio were observed to be higher in the patient group (p < 0.001). Conclusions: The inflammatory markers CRP and CRP/albumin ratio were found to be statistically significantly higher in the patient group. These parameters can be used to predict coronary slow flow in the emergency department.

Göğüs Ağrılı Hastaya Yaklaşım – Kardiyak Aciller Tufan ALATLI Göğüs Ağrılı Hastaya Yaklaşım Pulmoner AcillerSalih KOCAOĞLU Arrest Hastaya YaklaşımMuhammet ÇAKAS Senkop-PresenkopMeliha FINDIKÖzge KAMA BAŞCI Bradikardi TaşikardiRahime Sema TAŞ Nefes DarlığıKübra Nur GÜNEYSelman GÜMÜŞ Karın AğrısıFerhat ÇAY Bulantı-KusmaYağmur Ecem NURAYDIN Hematemez, Melena, HematokezyaAhmet Buğra ÖNLER HemoptiziHilal PINAR AteşHayrullah YURDAKUL Baş AğrısıSemih TAŞKINLAR Bilinç Bozukluğuna YaklaşımYeltuğ Esra GELEN Baş Dönmesine Acilde Yaklaşımİlker ÇERMİKLİ Hemiparezi, Hemipleji, ParaplejiFeyza Nur USLURahime Sema TAŞ Anemiye YaklaşımYaşar ŞİŞMAN Hipertansif Hastaya YaklaşımHarun GÜNEŞTürkay AKBAŞ Zehirlenmeye Genel YaklaşımHarun GÜNEŞEmine AYHAN AKMAN Anüri - HematüriSeçil AYDIN Anormal Uterin KanamaMeliha Miray ÇANTAL Acil DoğumDuygu LAFCIMurat BAŞCI Skrotal AğrıSümeyye KARABACAK Anorektal HastalıklarFerhat ÇAY Dermatolojik Acillere Yaklaşımİlkay CAN Döküntülü Bulaşıcı HastalıklarZekiye KANAT Ajite Hastaya YaklaşımMerve ŞAHİN CAN Çocuklarda ResüsitasyonÖzlem ÖZCANLI ÇAY Ateşli Çocuğa YaklaşımÖzlem ÖZCANLI ÇAY