Objective: To analyse the rate of occurrence and the clinical variables associated with readmission of patients who had previously been discharged after admission for COVID-19. Setting: University hospital in Madrid (Spain). Participants: Sixty-one patients (74% male) who presented COVID-19 were readmitted during the 3 weeks after discharge from hospital. Interventions: Nested case–control study paired (1:1 ratio) by age, sex and period of admission. Outcome Measures: Rate of readmission rate of patients discharged after suffering COVID-19 and identification of the clinical variables associated with it. Results: Out of 1368 patients who were discharged during the study period, 61 patients (4.4%) were readmitted. Immunocompromised patients (N=10.2%) were at increased risk for readmission (p=0.04). There was also a trend towards a higher probability of readmission in hypertensive patients (p=0.07). Cases had had a shorter hospital stay and a higher prevalence of fever during the 48 hours prior to discharge. There were no significant differences in oxygen levels measured at admission and discharge by pulse oximetry intra-subject or between the groups. Neutrophil-to-lymphocyte ratio at hospital admission tended to be higher in cases than in controls (p=0.06). Neither glucocorticoids nor anticoagulants prescribed at hospital discharge were associated with a lower readmission rate. Patients who were readmitted due to a thrombotic event (8 patients, 13.1%) presented a higher level of D-dimer at discharge of initial admission. Conclusion: The rate of readmission after discharge from hospital for COVID-19 was low. Immunocompromised patients and those presenting with fever during the 48 hours prior to discharge were at greater risk of readmission to hospital.

In this outbreak, 12 patients in intensive care units acquired a Chryseobacterium indologenes infection. Cultures from sinkholes and air samples were positive for C. indologenes. After removing wash basins, no new cases appeared. Sinkholes, potentially contaminated, can act as a reservoir for C. indologenes and other microorganisms. Thus, patients and equipment should be protected from sink splashes to avoid contamination.

Introducción: Las infecciones relacionadas con la asistencia sanitaria (IRAS) son un problema de Salud Pública prioritario en España y constituyen un marcador de calidad asistencial. La vigilancia de las IRAS ayuda a conocer la epidemiología de estas infecciones para orientar la implementación de adecuadas medidas de prevención y control. Metodología: se han analizado los datos individualizados de pacientes de la encuesta de prevalencia del 2022 (EP-2022), aportadas por la coordinación nacional del EPINE (Estudio de Prevalencia de las Infecciones Nosocomiales en España) de la Sociedad Española de Medicina Preventiva, Salud Pública y Gestión Sanitaria (SEMPSPGS), como parte de los acuerdos establecidos con el Ministerio de Sanidad. Se han calculado prevalencias de pacientes con alguna IRAS y con algún antimicrobiano (ATM) y se han analizado las asociaciones entre factores de riesgo de pacientes y características de hospitales con la presencia de IRAS. Resultados: La prevalencia de pacientes con alguna IRAS fue 8,2% y la de pacientes con algún ATM, 46,4%. Pacientes varones, entre 61-75 años, con hipoalbuminemia, úlceras por presión, coma, cirugía, catéter urinario o intubados, con un estado basal con categoría McCabe de “enfermedad tardía o rápidamente fatal”, ingresados en hospitales de 650 camas o más o en hospitales de larga estancia presentaron prevalencias más altas. Conclusiones: La EP-2022 ha permitido conocer la epidemiología de las IRAS en los hospitales españoles e identificar pacientes con potenciales factores riesgo donde maximizar esfuerzos de prevención de las infecciones.

Healthcare workers (HCWs) have been a critical and vulnerable population during SARS-CoV-2 pandemic. The aim of this study was to determine the overall seroprevalence and to evaluate occupational r...

Background: COVID-19 infection has led to an overwhelming effort by health institutions to meet the high demand for hospital admissions. Aim: To analyse the clinical variables associated with readmission of patients who had previously been discharged after admission for COVID-19. Design and methods: We studied a retrospective cohort of patients with laboratory-confirmed SARS-CoV-2 infection who were admitted and subsequently discharged alive. We then conducted a nested case-control study paired (1:1 ratio) by age, sex and period of admission. Results: Out of 1368 patients who were discharged during the study period, 61 patients (4.4%) were readmitted. Immunocompromised patients were at increased risk for readmission. There was also a trend towards a higher probability of readmission in hypertensive patients (p=0.07). Cases had had a shorter hospital stay and a higher prevalence of fever during the 48 hours prior to discharge. There were no significant differences in oxygen levels measured at admission and discharge by pulse oximetry intra-subject or between the groups. Neutrophil/lymphocyte ratio at hospital admission tended to be higher in cases than in controls (p=0.06). The motive for readmission in 10 patients (16.4%), was a thrombotic event in venous or arterial territory (p<0.001). Neither glucocorticoids nor anticoagulants prescribed at hospital discharge were associated with a lower readmission rate. Conclusions: The rate of readmission after discharge from hospital for COVID-19 was low. Immunocompromised patients and those presenting with fever during the 48 hours prior to discharge are at greater risk of readmission to hospital.