In facility horticultural production, intelligent disease recognition and precise intervention are vital for crop health and economic efficiency. We construct a multi-source dataset from Bayan Nur, Weifang, and Honghe that integrates handheld camera photos, drone field images, and laboratory-controlled samples. Handheld images capture fine lesion texture for close-up diagnosis common in greenhouses; drone images provide canopy-scale patterns and spatial context suited to open-field management; laboratory images offer controlled illumination and background for stable supervision and cross-crop feature learning. Our objective is robust cross-crop, cross-regional diagnosis and economically rational control. To this end, a model named CCGD-Net is proposed. It is designed as a multi-task framework. The framework incorporates a multi-scale perception module (MSFE) to produce hierarchical representations. It includes a cross-domain alignment module (CDAM) that reduces distribution shifts between greenhouse and open-field environments. The training follows an unsupervised domain adaptation setting that uses unlabeled target-region images. When such images are not available, the model functions in a pure generalization mode. The framework also integrates a regional economic strategy module (RESM) that transforms recognition outputs and local cost information into optimized intervention intensity. Experiments show an accuracy of 91.6%, an F1-score of 89.8%, and an mAP of 88.9%, outperforming Swin Transformer and ConvNeXt; removing RESM reduces F1 to 87.2%. In cross-regional testing (Weifang training → Honghe testing), the model attains an F1 of 88.0% and mAP of 86.5%. These results indicate that integrating complementary imaging modalities with domain alignment and economic optimization provides an effective solution for disease diagnosis across greenhouse and field systems.