Background: Ventral Pontine Syndrome, likewise called Millard Gubler Syndrome (MGS) or Facial abducens hemiplegia disorder is a neurodegenerative problem that is described by one-sided lesions influencing the basal piece of the caudal pons including fascicles of the abducens and the facial nerves and the pyramidal lot filaments. Clinical findings incorporate fringe Facial Nerve Paralysis and neuromuscular shortcoming or loss of motion of at least one appendage. This is an exceptionally uncommon condition assessed to influence 1 out of 10, 00, 000. Men (aged 40-60 years) are bound to foster the condition than ladies. Case Nuances: A 45-year-old male patient had intensely passed a-sided facial droop 4 days prior to presenting with weakness on the left half of his upper and lower appendages. He, along with his attender likewise referenced that he had recently had a 2-minute loss of cognizance, discombobulation, and vertical shifting of the right eye both when he lost his consciousness. He had low serum Vitamin D and was determined to have Millard Gubler Condition as an Infarct in the pontine locale was recognized in imaging, and was dealt with restoratively and with Non-intrusive treatment. Discussion: Millard-Gubler disorder might cause cerebellar ataxia if the paramedian pontine dead tissue region somewhat expands horizontally, influencing the centre cerebellar peduncles. Detached pontine localized necrosis might have decent progress whenever analyzed and overseen early. Conclusion: MGS is typically found in instances of brainstem cancers, drain, tuberculoma, parasitic contamination, Ischemic stroke secondary to impediment of the basilar supply route, and injury.
BackgroundGeneration Z students frequently encounter difficulties such as academic demands, prolonged exposure to screens, and psychological stressors, all of which adversely affect their sleep quality. This study investigates the behavioural and psychological elements that shape sleep patterns among individuals aged 18 to 24 in Andhra Pradesh, with particular emphasis on the timing of sleep onset, overall sleep duration, and the presence of sleep disturbances.Materials and MethodsA cross-sectional online survey was conducted using Google Forms, with a total of 932 participants involved. The primary objective of this survey was to collect data on a range of sleep-related parameters, which encompassed sleep latency, duration, disturbances, and various potential influencing factors, including academic pressures, screen time, and psychological stressors.ResultsWhile a majority of the students fell asleep within 30 min, a notable proportion experienced delays in falling asleep. The quantity of sleep reported by students varied widely, with many expressing that they failed to attain sufficient rest. Key factors that negatively impact sleep quality include heightened anxiety, academic stressors, and excessive engagement with electronic devices.ConclusionGeneration Z students in Andhra Pradesh face a decline in sleep quality due to a range of behavioural and psychological stressors, including academic demands, overuse of technology, and increased anxiety. By introducing targeted awareness programs and interventions that address these challenges, it is possible to improve sleep health and foster a more positive overall well-being for this group.
20 June 2025 in Indian Journal of Pharmacy Practice
Bell's palsy is an acute, idiopathic paralysis of the peripheral facial nerve, resulting in sudden unilateral facial weakness. It is often associated with viral infections, particularly herpes simplex, and is more common in adults than children. This case is notable as it involves a 13-year-old male with no prior illness or risk factors. A previously healthy 13-year-old male suddenly developed left-sided facial weakness, including an inability to fully close his left eye and a drooping mouth, without any history of trauma or illness. Neurological examination revealed left-sided facial nerve palsy, lagophthalmos, and Bell's phenomenon, with other cranial nerves unaffected. CT imaging ruled out intracranial abnormalities but showed bilateral maxillary and ethmoid sinusitis. A diagnosis of Bell's palsy was made based on clinical presentation and the exclusion of other conditions. The patient received a treatment regimen of 20 mg oral Prednisolone, 1000 mg Valacyclovir, and methylcobalamin. Supportive care included lubricating eye drops, protective eye taping during sleep, and physiotherapy for facial exercises. The patient was advised to return for reassessment in five days. Pediatric Bell's palsy usually has a positive prognosis, with most cases resolving within weeks to months. Early corticosteroid and antiviral treatment may enhance recovery. This case highlights the urgent need for prompt diagnosis and intervention in pediatric Bell's palsy to prevent complications and ensure optimal recovery. A thorough neurological assessment and appropriate imaging are essential to rule out other causes of facial paralysis.
1 September 2026 in Journal of Clinical and Diagnostic Research
Introduction: Abnormal Uterine Bleeding (AUB) has a profound impact on the reproductive health and overall quality of life of women. Although many causes have been identified, the role of regional, sociodemographic, and clinical factors is still not thoroughly examined in India. Aim: To assess the aetiological classification of AUB by employing the FIGO PALM-COEIN system. Materials and Methods: The present retrospective observational study investigated 384 cases of AUB at the Department of Obstetrics and Gynaecology, Government General Hospital, Guntur, Andhra Pradesh, from September 2024 to February 2025. The analysis involved data extracted from electronic and physical medical records, encompassing demographic, clinical, and diagnostic information. The causes were classified according to the FIGO PALM-COEIN criteria. Descriptive statistics were employed to encapsulate the demographic and clinical attributes of the study cohort. Categorical variables were represented as frequencies and percentages. Results: Among 384 women with AUB, the mean age was 38.9±7.6 years, with most patients aged 36-45 years (198, 51.6%). Overweight or obesity was observed in 245 subjects (63.8% of participants). The most frequent co-morbidities were hypothyroidism in 103 subjects (26.8%) and Polycystic Ovary Syndrome (PCOS) in 66 subjects (17.2%). AUB-L (Leiomyoma) in 119 subjects (31.0%), AUB-O in 97 subjects (Ovulatory dysfunction) (25.3%), and AUB-A (Adenomyosis) in 55 subjects (14.3%) were the predominant aetiologies. Significant associations were noted between AUB subtypes and age, early marriage, endocrine disorders, and nulliparity (p<0.05). Conclusion: According to the findings of the present study AUB in Indian women arises from multiple factors shaped by both structural and hormonal influences.
Background: Self-medication is the practice of treating any ailment or symptom that a person diagnoses for themselves without first visiting a physician. Different communities display different behaviours; hence the purpose of this study is to statistically investigate the patterns and prevalence of self-medication usage. Although health literacy practices have been increasingly recommended in public health literature, there is a lack of studies that examine the relationships between health literacy and self-medication. Methodology: A quantitative, descriptive, cross-sectional, community-based research approach was used in a sample of 316 participants. Health literacy was measured by Single Item Literacy Screener. Data was analysed using SPSS 29.0 version. Results: A total of 316 participants agreed to participate (63.9% were females). The results showed that more than half, 53.4% had adequate health literacy. The prevalence of self-medication was 74%, in these 52% had used medicines by previous prescription and 8% used alternative medicine. There was a significant relationship between the overall health literacy level and practice of self-medication. Conclusion: Improving the health literacy level of the public can reduce inappropriate self-medication Therefore, the design and implementation of training programs are necessary to increase the perception on the risk of self-medication. Appropriate reading skills are important for accessing health information, using health care services, and achieving desirable health outcomes.
23 August 2023 in International Journal of Medical and Pharmaceutical Case Reports
Background: Pulselessness is the main sign of Takayasu's Arteritis (TAK), a granulomatous large artery vasculitis that mostly affects the aorta, major aortic branches, and pulmonary arteries. Renal artery stenosis is the source of arterial hypertension, which is common in TA. It is estimated that there are 2.6 incidences of Takayasu's arteritis per million people worldwide each year. Case Details: We report on an 18-year-old girl whose significant arterial hypertension on her left arm, identified during a routine check-up, was the primary manifestation of Takayasu's arteritis (TA). The left arm's systolic blood pressure was noticeably greater than the right's. Additionally, there was a difference in blood pressure between the legs and left arm. Auscultation revealed the presence of vascular bruits over the left subclavian regions. A CT angiography was used to establish the diagnosis of TA. The results indicated a substantial constriction at the right renal artery's origin and characteristics compatible with aortic arteritis of the thoracic and abdominal aorta with active disease given wall enhancement. Due to the disorder's rarity and the varied ways in which it manifests clinically, a delayed diagnosis and treatment are likely. Conclusion: Our study emphasizes that this illness can and does affect young people, and as such, patients presenting with suggestive symptoms and signs—especially young patients with unexplained hypertension—should be taken into consideration. Appropriate imaging and clinical suspicion are essential for the accurate diagnosis and treatment of TA patients. Several findings were found during the clinical examination, including signs of claudication, fever symptoms, involvement of major vessels including the aorta and its branches. This illustrates the condition of Takayasu's arteritis and what medical professionals should anticipate when treating it.