The transverse grain boundaries in pure copper wires increase resistivity, generating capacitance and inductance effects, leading to a decrease in the electrical conductivity of pure copper wires. Directional heat treatment technology can eliminate transverse grain boundaries in pure copper conductors, which is of great significance for improving electrical conductivity. Directional heat treatment is essentially a secondary recrystallization process, with influencing factors involving microstructure, texture, etc. This study systematically investigated the effects of cold-drawing deformation rate and heat treatment processes on secondary recrystallization microstructure, grain boundary structure, and crystallographic texture in pure copper wires. The results demonstrate that higher deformation levels (≥89%) facilitate secondary recrystallization and enhance texture development. Moreover, the heat treatment temperature exerts a more significant influence on secondary recrystallization than the heat treatment duration. The grain coarsening temperature for pure copper wires with a deformation degree of 89% was determined to be 400 °C. These findings provide a fundamental basis for formulating directed heat treatment processes for pure copper wires.