Individualization of buildings is one of the key issues in the establishment of three-dimensional (3D) building models. Most existing individualization methods rely on inefficient manual separation, while deep learning approaches require extensive pre-training and are highly influenced by the spatial structure of the models. To address these issues, this paper proposes a novel method for 3D building individualization that integrates SAMPolyBuild with multiple spatial-geometric features. Leveraging the zero-shot learning capability of SAMPolyBuild, the method first performs coarse extraction of individual buildings, then refines the extraction accuracy using multiple spatial-geometric features. Innovatively, two statistical parameters—Jensen-Shannon Divergence and Earth Mover’s Distance—are introduced into the building identification process. To validate the feasibility and effectiveness of the proposed method, experiments were conducted on the Semantic Urban Meshes (SUM) dataset. The results demonstrate that the method can effectively extract individual building models from urban oblique photogrammetric 3D models, achieving an F1-score of approximately 0.83 for buildings with typical spatial structures.