Rosa Molfetta graduated in Biological Sciences from Sapienza University of Rome in 1997 and received a PhD in Immunology at the same place in 2003. Then, she worked as a Postdoctoral Research Fellow at the Department of Experimental Medicine, Sapienza University of Rome. She has been an Associate Professor at the Department of Molecular Medicine, Sapienza University of Rome since 2019. Her main research interests concern the molecular mechanisms regulating the expression and signaling of innate immune receptors and their ligands. In particular, she contributed to elucidating the role of the ubiquitin pathway in the regulation of internalization and trafficking of human NK cell-activating receptors as well as the high-affinity receptor for IgE in murine mast cells. More recently, she has focused on mast cells' role in tumor progression.