Background: The evolution of acute kidney injury (AKI) following coronary artery bypass grafting (CABG) operations may have several immediate effects on the health of the patients. Whether the preoperative C-reactive protein (CRP)/albumin ratio is a biomarker that can be used to predict the development of AKI after CABG is still under investigation. This study examined the ability of the CRP/albumin ratio to predict the risk of postoperative AKI. Methods: This study was a retrospective analysis of 186 patients who underwent CABG surgery at the Eskisehir City Hospital. Patients were categorized into low and high-risk groups based on preoperative CRP/albumin ratios. The diagnosis of AKI was based on an increase in serum creatinine level or oliguria according to the Kidney Disease Improving Global Outcomes (KDIGO) criteria. Preoperative CRP and albumin values, demographic characteristics, postoperative creatinine, estimated glomerular filtration rate (eGFR) and length of hospitalization were evaluated. Results: In patients who developed AKI, their CRP/albumin ratio was 2.48 (1.24–4.48), vs non-AKI patients; 1.21 (0.53–2.34); p < 0.001. The CRP/albumin area under the Receiver Operating Characteristic (ROC) curve (AUC) ratio in ciR was 0.782 with an AUC of 74.2% sensitivity and 71.8% specificity at a threshold value of 1.85. Patients who developed AKI also had a mean Intensive Care Unit (ICU) stay of 5 (3–8) days and a mean length of stay of 12 (9–18) days, which was longer than the control group, regardless of the cause of the hospitalization; (p < 0.001). Conclusion: High CRP/albumin ratio is an important risk marker for the development of AKI after CABG. Assessing the preoperative CRP/albumin ratio could be beneficial in predicting the risk of AKI and in devising appropriate postoperative management protocols for these patients.

Objective: This study aimed to investigate the prognostic value of the preoperative Inflammatory Prognostic Index (IPI) in predicting late mortality in patients undergoing isolated surgical aortic valve replacement (AVR). Methods: A retrospective, single-center cohort of 400 patients who underwent elective, isolated surgical AVR between 2015 and 2023 was analyzed. The IPI was calculated using the formula: C-reactive protein (CRP) × neutrophil-to-lymphocyte ratio (NLR) / albumin. Patients were stratified into low- and high-IPI groups based on an optimal cut-off value of 0.2588 determined via ROC analysis. Clinical characteristics, operative data, and outcomes were compared. Cox proportional hazards regression was used to identify independent predictors of late mortality. Results: Patients with high IPI scores (≥0.2588) had significantly increased late mortality compared to those with low IPI (<0.2588) (10.3% vs 2.3%, p < .001). High IPI was associated with elevated CRP and neutrophils, and reduced albumin and lymphocytes. In univariate analysis, age, bioprosthesis use, and high IPI were significantly associated with late mortality. However, in multivariate analysis, only high IPI remained an independent predictor (HR = 3.405, 95% CI: 1.289–8.996, p = .013). Kaplan–Meier survival analysis confirmed lower long-term survival in the high-IPI group ( log-rank p < .001). Conclusion: Preoperative IPI is a simple, accessible, and independent predictor of late mortality after surgical AVR. Integrating IPI into preoperative risk assessment may improve long-term prognostic stratification and guide perioperative management.

Background: Approaches that require less invasive procedures, offer heal in a shorter time and provide better cosmetic results have gained importance with the technological and modern developments in cardiac surgery. Esthetically preferred results can be achieved after heart valve surgery using a periareolar incision, especially in female patients. In the present study, we aimed to present our results after surgery using periareolar incision in female patients. Methods: We retrospectively evaluated the 1-year follow-up results in the postoperative period of isolated mitral valve replacement and tricuspid valve repair with mitral valve replacement using a periareolar incision with direct observation in 32 patients between 2020 and 2023. At the end of 1-year follow-up, we evaluated the patients’ visual satisfaction with the incision site using a visual analog scale. Results: According to the postoperative follow-up results, no prosthetic mitral valve dysfunction was detected in any of the patients at the 1st year echocardiography controls. Mild tricuspid valve insufficiency was detected in 3 patients who underwent tricuspid valve repair. Besides, a high level of satisfaction was observed in the patients’ incision site evaluations with a visual analog scale at the end of the first year, and no numbness was reported in the periareolar region in any of the patients. Conclusion: Our study shows that surgical results similar to conventional methods can be achieved with the periareolar approach, and patient satisfaction and recovery times are shorter and more satisfying. We also think that the periareolar incision can be made without videoassisted equipment and this may reduce the surgical cost.

Background: Intermittent Claudication (IC) is exercise pain seen in lower extremity arterial diseases. If it is left untreated, it may be the initial sign of a process leading to amputation. In the present study, the purpose was to compare the postoperative early and mid-term results of the patients who were treated with endovascular methods and those who underwent bypass graft surgery in the treatment due to IC complaints because of isolated Femoropopliteal Arterial Disease. Method: Postoperative first-month, sixth-month, and 12th-month follow-up results, procedure requirements, and demographic characteristics of the 153 patients who underwent femoropopliteal bypass because of isolated Femoropopliteal Arterial Disease and 294 patients who underwent endovascular intervention in our hospital between January 2015 and May 2020 were compared in the study. Results: It was found in demographic characteristics that endovascular intervention was performed more frequently in smokers and graft bypass surgery was performed more frequently in hyperlipidemic patients, and the results were found to be statistically significant. High amputation rates were detected at statistically significant levels in diabetic and hypertriglycemic patients and 1-year primary patency rates were found to be higher in patients who underwent graft bypass surgery. No differences were detected between the two methods in terms of mortality. Conclusion: Interventional treatment modalities must be considered for patients with isolated Femoropopliteal Arterial Disease whose symptoms persist despite exercise and the best medical treatment. We think that Bypass Graft Surgery has more positive results than endovascular interventions when short and medium-term amputation, repetitive intervention needs, and changes in quality of life are compared in patients who receive the same medical treatment.