Summary: Purpose: To study the mechanisms of startle‐induced supplementary sensorimotor area (SSMA) seizures. Methods: We present a patient investigated with indwelling subdural grid electrodes covering both the SSMA and the dorsolateral frontal lobe. Results: We found a simultaneous seizure onset in the right dorsolateral premotor cortex and the right SSMA. High‐resolution magnetic resonance imaging (MRI) showed a small subcortical lesion adjacent to the right SSMA. The patient became seizure free after resection of the lesion and the ictalonset zone. Conclusions: We conclude that an extended region of abnormally excitable tissue within the frontal lobe could facilitate the generation of startle‐induced seizures. We speculate that a widespread epileptogenic zone could help to explain why some patients with SSMA or dorsolateral frontal lobe seizures are more likely to have startle‐induced seizures.
12 February 2022 in Seizure: European Journal of Epilepsy
We report on a 7-year-old girl with drug-resistant occipital lobe epilepsy due to focal cortical dysplasia who was initially misdiagnosed as suffering from migraine. We also discuss the diagnostic steps, including clinical semiology, electrophysiology and imaging, particularly with respect to the differential diagnosis of parietal lobe epilepsy.