The increasing incidence of cancer worldwide is multifactorial, attributable to population longevity, changing environmental and lifestyle factors, and increased surveillance. Thyroid cancer is a prime example for which intensified surveillance has resulted in an increasing incidence of early cancers with indolent behavior,^1,2 a phenomenon commonly described as cancer “overdiagnosis.”³ The increasing incidence is solely attributable to papillary thyroid carcinoma (PTC), a tumor named for its papillary growth pattern, although the defining diagnostic criteria are actually the nuclear features of neoplastic cells.⁴ Aside from the enhanced screening, another important factor contributing to this phenomenon is the increase in diagnosis of a variant of PTC known as the follicular variant of PTC (FVPTC).⁵