Authors’ contribution Study conception and experimental design: Yu-Kai Su. Performed the experiments: Oluwaseun Adebayo Bamodu. Data collation and analysis: Wei-Hwa Lee, Yu-Kai Su. and Chi-Tai Yeh. Manuscript writing: Yu-Kai Su, Iat-Hang Fong and Hsiao-Yean Chiu. Provided reagents, materials, and experimental infrastructure: I-Chang Su, Chi-Tai Yeh, and Chien-Min Lin. All authors read and approved the final submitted version of the manuscript.