Land use change is extremely sensitive to natural factors and human influence in active debris flow. It is therefore necessary to determine the factors that influence land use change. This paper took Wudu District, Gansu Province, China as a study area, and a systemic analysis of the transformational extent and rate of debris flow waste-shoal land (DFWSL) was carried out from 2005 to 2015. The results show that from 2005 to 2015, cultivated land resources transformed to other types of land; cultivated lands mainly transformed to grassland from 2005 to 2010 and construction land from 2010 to 2015. Moreover, the growth rate of construction land from 2005 to 2010 was only 0.11%, but increased to 6.87% between 2010 and 2015. The latter is more than 60 times the former. This increase was brought about by natural disasters (debris flow, earthquakes, and landslides) and anthropogenic factors (national policies or strategies), which acted as driving forces in debris flow area. The former determines the initial use type of the DFWSL while the latter only affects the direction of land use and transformation.