Ming-Liang Lai

Dr. Ming-Liang Lai

orcid

Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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13 June 2023 in IEEE Transactions on Engineering Management
Verified
Journal Article
Closed access
MLMing-Liang Lai
Ming-Liang Lai
Many countries use the offshore wind power technology as renewable energy for sustainable development. In this study, we will focus on the knowledge dissemination of the offshore wind power technology. Not every country has the ability to develop their own offshore wind power technologies. The knowledge dissemination on sustainable technology could bridge the technology gap among the developer and promote the development of sustainable clean energy technology. Some objective evaluation indicators of knowledge dissemination will be carried out in this research and help to find appropriate companies to assist the local industry on offshore wind power industry. The public patent information is used to build a model to bring evaluation indicators about knowledge dissemination. These evaluation indicators include the revealed symmetric technological advantage index (RSTA), the knowledge density index ( Dc,m,t ), and the relatedness knowledge base index ( Rc,r,t ). For RSTA, D and R indicators, Siemens Aktiengesellschaft, Vestas Wind Systems, Siemens Gamesa Renewable Energy, and Aloys Wobben have higher values, which can be evaluated to have the higher degree of knowledge dissemination in the field of offshore wind power technology. Unlike previous studies that only using patent bibliographic data alone, employ evaluation indicators can extract more information about the knowledge dissemination. This study presents a promising method to evaluate the degree of knowledge dissemination in offshore wind power technology by using patent data.

11 December 2025 in Microorganisms
Verified
Journal Article
Open access
PDF file
Mutebi John KennethMutebi John Kenneth
Mutebi John Kenneth
CFChuan-Yin Fang
Chuan-Yin Fang
CWChin Chia Wu
Chin Chia Wu
MHMing-Chih Hsieh
Ming-Chih Hsieh
MLMing-Liang Lai
Ming-Liang Lai
BHBing-Mu Hsu
Bing-Mu Hsu
Recent studies indicate that opportunistic gut bacteria contribute to the recurrence and chemoresistance in colorectal cancer (CRC); however, their fate after surgical resection remains poorly understood. This study investigated the longitudinal changes in these bacteria and assessed their potential persistence following CRC surgery. Forty fecal samples were collected from ten CRC patients at four timepoints: (1) pre-surgery (S); (2) one week (S1); (3) one month (S2); and (4) three months (S3) post-surgery. Fifteen other fecal samples were collected from healthy individuals as our study controls. Microbial profiling was performed using 16S rRNA gene sequencing, and quantitative PCR was applied to assess the changes in three opportunistic bacteria associated with CRC-associated. Our study revealed that Escherichia coli was significantly enriched in pre-surgical samples (S), while Enterococcus faecalis was predominant in the samples collected one-week after surgery (S1). All the assessed species showed a gradual post-surgical decline in relative abundance, suggesting they do not persist after resection. Additionally, there was a significant increase in relative abundance of beneficial bacterial signatures, including Akkermansia muciniphila, Bacteroides uniformis, Parabacteroides merdae, and Phascolarctobacterium faecium post-surgery, which implies a potential dysbiosis restoration. Our findings suggest that surgical resection gradually reduces the burden of opportunistic gut microbiota, thus gradually lowering the risk of recurrence and chemoresistance. Additionally, it may facilitate the restoration of beneficial taxa. Future studies should include extended follow-up periods to validate our findings and their correlation with clinical outcomes.