Malaria is a significant public health challenge in the Democratic Republic of the Congo (DR Congo), with a high prevalence and mortality rate, particularly among children under five years old. This study examines the impact of malaria in eastern DR Congo, where armed conflict and humanitarian crises have resulted in overcrowded refugee and internally displaced persons (IDP) camps, exacerbating malaria transmission. Malnutrition, limited access to healthcare, and poor living conditions makes children under the age of five particularly vulnerable. Despite attempts by organizations such as the World Health Organization and various non-governmental organizations to supply insecticide-treated bed nets and antimalarial drugs, implementation in refugee camps is impeded by war, resource constraints, and insufficient healthcare facilities. A focused elimination approach that includes integrated vector control, enhanced diagnostic access, healthcare professional training, and community engagement is critical. Surveillance and research are critical for determining malaria prevalence and resistance patterns. Effective malaria treatment in refugee camps necessitates broad strategies to protect vulnerable children and lower disease burdens.

Endocrine disruptors (EDs) are a heterogeneous group of natural or synthetic chemicals capable of interfering with hormonal regulation. Widely present in plastics, cosmetics, pesticides, food packaging, and household products, they contribute to constant human exposure. Compounds such as bisphenol A, phthalates, parabens, dioxins, and certain pesticides are among the most studied. Their mechanisms of action include interaction with hormone receptors, modulation of gene expression through epigenetic changes, disruption of steroidogenesis, and interference with the hypothalamic–pituitary–gonadal axis. Evidence from animal and human studies suggests that EDs may reduce ovarian reserve, impair oocyte maturation, alter ovulation and implantation, and contribute to infertility. Associations have also been observed with polycystic ovary syndrome, endometriosis, and poorer outcomes of assisted reproductive techniques. Despite these findings, human data remain largely observational, with methodological limitations such as variable exposure assessment, lack of standardized biomarkers, and the unaddressed “cocktail effect.” Strengthening preventive strategies, regulatory measures, and further research is essential to better understand and mitigate the risks EDs pose to female reproductive health.

Malaria remains a significant public health challenge in the Democratic Republic of Congo (DR Congo), particularly among pregnant women and children under 5, who bear the highest burden of disease and mortality. Despite efforts to scale up control programs, the country faces numerous challenges, including limited healthcare access, inadequate funding, insecticide resistance, and gaps in surveillance. Vector control efforts are constrained by minimal government involvement and heavy reliance on international donors. Recent innovations, such as genomic surveillance, rapid diagnostic tests (RDTs), and mobile health (mHealth) solutions, offer new avenues for improving diagnosis, treatment, and data collection. Integrated approaches, such as incorporating malaria prevention into routine maternal and child healthcare, expanding access to vaccines like RTS,S and R21, and improving the distribution of long-lasting insecticidal nets (LLINs), are vital for sustaining control efforts. Community engagement and behavior change strategies are crucial to increasing uptake of preventive measures. Furthermore, climate change necessitates adaptable interventions to address shifting transmission patterns. Strengthening surveillance, training community health workers, and fostering public-private-philanthropic partnerships will enhance capacity for malaria control. Sustainable financing, policy reinforcement, and innovative tools are essential to prevent resurgence and protect vulnerable populations, ensuring progress toward malaria elimination in DR Congo. This review uniquely aims to address and consolidate evidence on pregnant women and young children in the DR Congo context, highlighting innovations and donor-dependence risks.”

Background: The Democratic Republic of Congo (DRC) faces a “triple burden” of public health threats which includes climate change, protracted armed conflict, and the under‐recognized spread of arboviral diseases. Arboviruses, such as dengue, chikungunya, Zika, and yellow fever, are transmitted by Aedes aegypti and Aedes albopictus mosquitoes. Certain factors, like environmental changes, population displacement, and inadequate vector control, have created conditions that favor sustained transmission. Methods: The narrative review was conducted to compile evidence on factors influencing arbovirus spread in the DRC and to identify the priority causes of prevention. A comprehensive literature search was done in PubMed and Google Scholar for studies, NGO reports, and government documents published between 2019 and 2025 in French or English, focusing on human populations in the DRC or similar contexts. Results: Key findings demonstrate that yellow fever remains endemic, with recurrent outbreaks and a case fatality rate of up to 21.3% in past years. Seroprevalence studies show significant dengue exposure (up to 41% in Kinshasa), multiple chikungunya epidemics which affected millions, and intermittent Zika virus exposure. On the other hand, adverse climate change alters vector ecology and increases transmission potential through drought, floods, rising temperatures, and deforestation. Armed conflict proved to play a major role in the large‐scale displacement of people into overcrowded, unsanitary environments. This, as a result, disrupts the surveillance and control programmes and increases vulnerability to arboviruses. Conclusion: The convergence of climate change, armed conflict, and arbovirus transmission poses a growing public health threat in the DRC. Strengthening integrated and reinforced surveillance, augmenting diagnostic capacity, applying sustainable vector control, and advocating climate and security considerations in health policy are essential and mandatory. Without coordinated and multidisciplinary action, the silent and hazardous spread of arboviruses will remain consistent to weaken and compromise health system resilience.