Pierre-Marie GIRARD obtained his Ph.D in 1995 in biophysics at UPMC (Paris, France). During his Ph.D. (Institut Gustave Roussy, Villejuif, France), he studied the self-dimerization of short RNA molecules derived from the genomic RNA of retroviruses. He then moved to the DNA repair field by joining the lab of Dr S. BOITEUX from 1996 to 1998 (CEA, Fontenay-aux-Roses, France) to study in vitro the repair of 8-oxoG. He studied a second post-doc at the GDSC (Sussex, UK) in the group of P. JEGGO (from 1998 to 2002), during which he studied DSB repair and cell cycle checkpoint activation in mammalian cells in response to IR. PM GIRARD was recruited at the CNRS in 2002 and joined the team of E. SAGE at Institute Curie (Orsay, France) to study the cellular response to UVA radiation and the role of UVA-induced ROS. In 2015, he joined the group of M. DUTREIX (Orsay, France) to better characterize the antitumor effect of AsiDNA, a small DNA repair inhibitor developed in the team, in combination with radiotherapy, especially FLASH radiotherapy. He also collaborates with physicists to examine the potential of using cold atmospheric pressure plasma as an innovative anticancer treatment.
Research Keywords & Expertise
Cancer Treatment
Cell Cycle
Chemotherapy
DNA damage
DNA Repair
ROS
radiotherapy
Innovative therapies
Cold pressure plasma t...
Fingerprints
36%
DNA Repair
36%
ROS
29%
DNA damage
22%
Cell Cycle
15%
Chemotherapy
15%
radiotherapy
8%
Cancer Treatment
8%
Cold pressure plasma therapy
Short Biography
Pierre-Marie GIRARD obtained his Ph.D in 1995 in biophysics at UPMC (Paris, France). During his Ph.D. (Institut Gustave Roussy, Villejuif, France), he studied the self-dimerization of short RNA molecules derived from the genomic RNA of retroviruses. He then moved to the DNA repair field by joining the lab of Dr S. BOITEUX from 1996 to 1998 (CEA, Fontenay-aux-Roses, France) to study in vitro the repair of 8-oxoG. He studied a second post-doc at the GDSC (Sussex, UK) in the group of P. JEGGO (from 1998 to 2002), during which he studied DSB repair and cell cycle checkpoint activation in mammalian cells in response to IR. PM GIRARD was recruited at the CNRS in 2002 and joined the team of E. SAGE at Institute Curie (Orsay, France) to study the cellular response to UVA radiation and the role of UVA-induced ROS. In 2015, he joined the group of M. DUTREIX (Orsay, France) to better characterize the antitumor effect of AsiDNA, a small DNA repair inhibitor developed in the team, in combination with radiotherapy, especially FLASH radiotherapy. He also collaborates with physicists to examine the potential of using cold atmospheric pressure plasma as an innovative anticancer treatment.