Background/Objectives: Cardiovascular diseases remain the leading cause of death among women, with peripheral arterial disease (PAD) representing an important manifestation of systemic atherosclerosis. The ankle–brachial index (ABI) is a simple, non-invasive measure used for PAD screening and cardiovascular risk assessment. This study aimed to compare ABI values between women of reproductive and postmenopausal age and to explore associations with lifestyle and clinical characteristics in primary care settings. Methods: This cross-sectional study included 437 women recruited from family medicine offices in two Croatian counties between November and December 2024. Participants completed validated questionnaires on dietary habits (MEDAS) and physical activity (IPAQ/PASE), and underwent anthropometric and blood pressure measurements. ABI was assessed using an automated MESI device following a standardized protocol. Multivariable logistic regression was performed to identify independent predictors of abnormal ABI (<1.00), adjusting for age, BMI, hypertension, smoking, and county. Results: Most participants had normal ABI values (right 95.7%; left 95.0%). Mild to moderate PAD (ABI 0.90–0.99) was observed in approximately 3% and severe PAD (ABI < 0.90) in ≤1.1% of cases. Postmenopausal women were more likely to present with lower ABI values (p = 0.046), though this association was attenuated after adjusting for age. Lifestyle factors, including diet and physical activity, showed no significant association with ABI in the adjusted models. Conclusions: Age emerged as the primary determinant of reduced ABI, while hypertension and smoking showed positive but non-significant associations. The findings underscore the importance of early vascular screening and lifestyle-based prevention in women, particularly in the postmenopausal period. Larger longitudinal studies are warranted to clarify causal pathways and the role of hormonal and behavioral factors in peripheral arterial disease development.

Background: Postpartum depression (PPD) is a common perinatal mental health disorder with important consequences for mothers and children. Early detection depends largely on primary and community healthcare professionals. This study assessed knowledge, recognition patterns, and screening practices related to PPD and examined factors associated with screening implementation. Methods: An exploratory cross-sectional online survey using convenience sampling was conducted between December 2025 and March 2026 among 154 healthcare professionals (74 community nurses and 80 physicians). Structured questionnaires assessed PPD knowledge, while physicians additionally reported screening and treatment practices. Group differences, correlations, and predictors of screening implementation were analyzed statistically. Results: Community nurses achieved higher overall knowledge scores than physicians (66.1% vs. 58.4%; p = 0.0038). Physicians more frequently distinguished baby blues from PPD (60.0% vs. 27.0%; p < 0.001). Awareness of validated screening tools among physicians was low, with only 10.0% recognizing the EPDS. Although physician knowledge correlated with screening frequency before correction for multiple testing (ρ = 0.27; p = 0.015), the association was not statistically significant after BH–FDR correction (q = 0.075). In multivariable logistic regression analysis, guideline awareness was not significantly associated with screening implementation (OR = 3.81; 95% CI 0.98–14.82; p = 0.053). Conclusions: Gaps remain in knowledge of PPD screening tools and treatment, particularly among physicians. The findings support the need for improved education, dissemination of clinical guidelines, and implementation support for standardized screening practices. However, given the exploratory convenience-sampling design and the lack of statistically significant adjusted associations, further longitudinal and implementation-focused studies are needed.

Background: Toxic shock syndrome (TSS) is a rare but potentially fatal condition most often caused by Staphylococcus aureus or Streptococcus pyogenes. However, other streptococcal species, including Streptococcus agalactiae (group B Streptococcus (GBS)), can also cause TSS, sometimes leading to severe complications, such as multiorgan failure. Case Description: We report the case of a 45-year-old woman who developed TSS associated with tampon use. She presented with fever, chills, hypotension, and leg pain, progressing rapidly to septic shock and multiorgan failure. Blood and urine cultures revealed S. agalactiae group B, while a gynecological examination identified Ureaplasma urealyticum and S. agalactiae. Imaging demonstrated bilateral pneumonic infiltrates and pleural effusion. The patient required intensive care, vasopressor support, and broad-spectrum antibiotic therapy, leading to full clinical recovery. Discussion: Despite advances in tampon design, menstrual TSS remains a significant clinical concern. Early symptoms may be nonspecific, but rapid progression highlights the need for timely recognition and intervention. Although S. agalactiae is an uncommon cause of TSS, it should be considered in relevant clinical scenarios. Prompt empirical antibiotic therapy, followed by targeted treatment based on culture results, along with supportive intensive care, is essential to improve outcomes. Conclusions: Menstrual TSS continues to pose a serious health risk. Physicians should maintain a high index of suspicion in tampon users presenting with fever, rash, and shock. Early diagnosis and rapid initiation of appropriate therapy are crucial to reducing morbidity and mortality.