Background/Objectives: The ¹⁰³Pd/^103mRh in vivo generator represents a promising Auger electron-emitting system, in which both parent and daughter radionuclides emit predominantly Auger electrons with minimal accompanying radiation. This study investigates the release dynamics of daughter radionuclides from the ¹⁰³Pd/^103mRh in vivo generator and evaluates the underlying mechanisms governing bond rupture and daughter retention. Methods: Cyclotron irradiation of rhodium foils was performed in two separate batches, followed by radionuclide separation using conventional wet chemistry and a novel dry distillation technique. The purified ¹⁰³Pd radionuclide was used to radiolabel DOTA-TATE, phthalocyanine-TATE, and DOTA-TOC chelators. The resulting complexes were immobilized on Strata-X and Strata-C18 solid-phase extraction columns. Scheduled elution experiments were conducted to quantify the release of the ^103mRh daughter radionuclide. Results: The measured ^103mRh release rates were 9.8 ± 3.0% and 9.6 ± 2.7% from Strata-X columns with DOTA-TATE and phthalocyanine-TATE, respectively, and 10.5 ± 2.7% and 12.0 ± 0.5% from Strata-X and Strata-C18 columns, respectively, with DOTA-TOC. These values are significantly lower than the ~100% release predicted based on the reported Auger electron yield of 186%. One explanation for this difference could be potential inconsistencies in decay data that may require correction; this needs further investigation. The results further demonstrated that delocalized π-electrons, introduced via phthalocyanine-based chelation, did not mitigate daughter release. Conclusions: The low observed daughter nuclide release represents a favorable characteristic for the future clinical translation of the ¹⁰³Pd/^103mRh Auger emitter pair. The findings support the conclusion that Auger electron cascades, rather than nuclear recoil energy, dominate bond rupture processes.

A method for the production of ¹¹¹In from an antimony target irradiated with 600 MeV protons has been developed. Here, a three-stage scheme of indium purification using ion-exchange chromatography is performed. The radiochemical yield is 85%, with a decontamination factor of the target material of no less than 10⁹. The ¹¹¹In preparation produced by the present method was used in studies of perturbed angular correlations. Also, a procedure for the production and separation of ^117mSn/^119mTe was developed, which is of particular interest for further studies on designing a generator to produce ¹¹⁹Sb.

Phosphoric acid is an important industrial chemical used in the manufacture of fertilizers, food-grade products, detergents and pharmaceuticals.[1–3] It is widely employed in a variety of analytica...

The present study reports the production of low radioactive tin-lead solder (at a ratio of 60% to 40%) based on archaeological lead. The solder can be employed in low-background experiments, which search for dark matter and the neutrinoless double beta decay using the bolometric method. The product impurity content has been estimated via low-background gamma spectrometry. The specific activity of the ²³⁸U, ²³²Th, and ⁴⁰K isotopes in the synthesized solder was below the minimum detection activity of the spectrometer (⁴⁰K < 1.24 mBg/kg, ²³²Th < 2 mBg/kg and ²³⁸U < 8.6 mBg/kg).