Kounis syndrome is a condition characterized by temporary coronary spasm, reduction in coronary blood flow and myocardial ischemia by activated mast cells as a result of an abnormal immune reaction to a drug or molecule. It is also called allergic angina and allergic myocardial infarction. It was first described by Kounis and Zarvas in 1991. (1) Kounis syndrome can be observed in all age groups regardless of the history of coronary artery disease. Kounis syndrome may occur due to environmental factors such as drugs, intracoronary stent implantation, foods, insect bites, bee stings, pollen, latex exposure etc. In our case report, acute coronary syndrome occurring during anaphylaxis secondary to vitamin B and C infusion, which is frequently used in clinical practice, will be explained.

Background: Obstructive sleep apnea syndrome (OSAS) is associated with sympathetic overactivity, intermittent hypoxia, and increased vascular resistance, leading to cardiovascular morbidity. Electrical cardiometry (EC) is a novel, non-invasive technology that continuously measures hemodynamic parameters such as systemic vascular resistance (SVR), systemic vascular resistance index (SVRI), cardiac output (CO), and cardiac index (CI). The aim of this study was to compare SVR and SVRI values, measured by EC, between patients with OSAS and age- and sex-matched healthy controls. Methods: In this retrospective case–control study, 70 participants were enrolled, including 33 patients with polysomnography-confirmed OSAS and 37 healthy controls matched for age and sex. All participants underwent standard EC measurement (ICON^® Cardiotronics, Osypka Medical, GmbH, Berlin, Germany) under resting, supine conditions. Hemodynamic parameters such as SVR, SVRI, and CI were compared between groups. Results: EC revealed significantly higher SVR (1498.7 ± 335.6 vs. 1260.1 ± 251.5 dyn·s·cm⁻⁵, p = 0.013) and SVRI (2969.4 ± 749.1 vs. 2347.4 ± 481.0 dyn·s·cm⁻⁵·m², p < 0.001) in patients with OSAS compared with controls, while CI was significantly lower in the OSAS group (2.6 ± 0.5 vs. 3.2 ± 0.8 L/min/m², p < 0.001), indicating increased vascular load and reduced cardiac performance. Conclusions: This study is the first to apply EC in OSAS. EC-derived parameters, particularly SVRI and CI, effectively differentiated OSAS patients from healthy subjects, reflecting increased vascular afterload and reduced cardiac performance. These findings suggest that EC is a feasible, non-invasive tool for assessing hemodynamic alterations in OSAS and may have potential for bedside monitoring and future risk stratification studies.

Objective: Myocardial bridging (MB) is a congenital anomaly in which an epicardial coronary artery courses intramyocardially. MB-related compression is often asymptomatic but can rarely cause sudden cardiac death, arrhythmia, or ischemia. This study aimed to investigate the prevalence, demographic characteristics, and gender differences of MB. Materials and Methods: A total of 2950 patients who underwent invasive coronary angiography (CA) were retrospectively evaluated. Clinical characteristics, biochemical/hematological parameters, and angiographic findings were compared between genders. Results: MB was identified in 119 (4%) patients, of whom 75 (63%) were males and 44 (37%) were females. The mean age of patients was 61.4±10.6 yr. Among patients with MB, 60.5% had hypertension, 31.9% had diabetes mellitus, 53.8% had coronary artery disease, and 47.9% were smokers. MB was most frequently detected in the mid segment of the left anterior descending artery (LAD) in 61 patients (51.3%). No significant gender differences were observed in MB length, vessel distribution, or compression rate. Conclusion: MB is not an uncommon finding during invasive CA in middle-aged patients. The prevalence was 4% in our study. The most common site was the mid segment of the LAD. No gender-based differences were observed in MB length, vessel distribution, or compression rate.