Jung-Wook PARK

Prof. Jung-Wook PARK

Yonsei University
orcid

Research Focus & Metrics

Academic Career Length

24Years (2003-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 April 2016 in Cancer Cell
Verified
Journal Article
Closed access
JLJohn K. Lee
John K. Lee
JPJohn W. Phillips
John W. Phillips
BSBryan A. Smith
Bryan A. Smith
Jung-Wook PARKJung-Wook PARK
Jung-Wook PARK
TSTanya Stoyanova
Tanya Stoyanova
OWOwen N. Witte
Owen N. Witte

5 October 2018 in Science
Verified
Journal Article
Closed access
PDF file
Jung-Wook PARKJung-Wook PARK
Jung-Wook PARK
JLJohn K. Lee
John K. Lee
KSKatherine M. Sheu
Katherine M. Sheu
LWLiang Wang
Liang Wang
NBNikolas G. Balanis
Nikolas G. Balanis
OWOwen N. Witte
Owen N. Witte
Some (re)programming notes on cancer: Epithelial cancers develop resistance to targeted therapies in a number of different ways. Several cancer types do so by undergoing phenotypic conversion to a highly aggressive cancer called small cell neuroendocrine carcinoma (SCNC). Whether distinct cancer types accomplish this “reprogramming” through the same mechanism has been unclear. Park et al. show that the same set of oncogenic factors transforms both normal lung and normal prostate epithelial cells into SCNCs that resemble clinical samples (see the Perspective by Kareta and Sage). This convergence of molecular pathways could potentially simplify the development of new therapies for SCNC, which is currently untreatable. Science , this issue p. 91 ; see also p. 30

17 April 2012 in IEEE Transactions on Power Delivery
Verified
Journal Article
Closed access
GSGum Tae Son
Gum Tae Son
HLHee-Jin Lee
Hee-Jin Lee
TNTae Sik Nam
Tae Sik Nam
YCYong-Ho Chung
Yong-Ho Chung
ULUk-Hwa Lee
Uk-Hwa Lee
Jung-Wook PARKJung-Wook PARK
Jung-Wook PARK
This paper presents design and control methods for fault-tolerant operations with redundant converter modules, one of the most prominent features in modular multilevel converter (MMC) topology. In fully implementing MMC functionalities, a nearest level control is applied as a low-switching modulation method. A dual sorting algorithm is newly proposed for effectively reducing the switching commutations of each power module as well as for voltage balancing control. Built upon these primary MMC topological and control features, its redundant operation is comprehensively investigated for fail-safe energy transfer. In particular, a novel spare process is proposed to handle an emergency situation when the number of faulty power modules exceeds the module redundancy. Since topological redundancy may cause the switching commutations of power modules in an arm to be unevenly distributed, a practical and effective mitigation measure is incorporated to keep the energy balance while avoiding the undesired switching stresses. Rigorous simulation studies for MMC and its application for high-voltage direct current are performed to demonstrate the validity and effectiveness of the proposed spare process under normal and emergency conditions.

1 July 2019 in Cancer Cell
Verified
Journal Article
Closed access
NBNikolas G. Balanis
Nikolas G. Balanis
KSKatherine M. Sheu
Katherine M. Sheu
FEFavour N. Esedebe
Favour N. Esedebe
SPSaahil J. Patel
Saahil J. Patel
BSBryan A. Smith
Bryan A. Smith
TGThomas G Graeber
Thomas G Graeber

25 January 2016 in IEEE Transactions on Power Systems
Verified
Journal Article
Closed access
MKMoses Kang
Moses Kang
KKKeonhui Kim
Keonhui Kim
EMEduard Muljadi
Eduard Muljadi
Jung-Wook PARKJung-Wook PARK
Jung-Wook PARK
YKYong Cheol Kang
Yong Cheol Kang
This paper proposes a torque limit-based inertial control scheme of a doubly-fed induction generator (DFIG) that supports the frequency control of a power system. If a frequency deviation occurs, the proposed scheme aims to release a large amount of kinetic energy (KE) stored in the rotating masses of a DFIG to raise the frequency nadir (FN). Upon detecting the event, the scheme instantly increases its output to the torque limit and then reduces the output with the rotor speed so that it converges to the stable operating range. To restore the rotor speed while causing a small second frequency dip (SFD), after the rotor speed converges the power reference is reduced by a small amount and maintained until it meets the reference for maximum power point tracking control. The test results demonstrate that the scheme can improve the FN and maximum rate of change of frequency while causing a small SFD in any wind conditions and in a power system that has a high penetration of wind power, and thus the scheme helps maintain the required level of system reliability. The scheme releases the KE from 2.9 times to 3.7 times the Hydro-Québec requirement depending on the power reference.

23 April 2018 in Proceedings of the National Academy of Sciences
Verified
Journal Article
Open access
PDF file
JLJohn K. Lee
John K. Lee
NBNathanael J. Bangayan
Nathanael J. Bangayan
TCTimothy Chai
Timothy Chai
BSBryan A. Smith
Bryan A. Smith
TPTiffany E. Pariva
Tiffany E. Pariva
OWOwen N. Witte
Owen N. Witte
Significance: Advanced prostate cancer is a deadly disease made up of multiple cancer subtypes that evolve during its natural history. Unfortunately, antibody- and cell-based therapies in development that target single tumor antigens found in conventional prostate cancer do not account for this heterogeneity. Here, we show that two major subtypes of advanced prostate cancer, prostate adenocarcinoma (PrAd) and neuroendocrine prostate cancer (NEPC), exhibit distinct cell-surface expression profiles. Integrated analysis of gene expression and cell-surface protein expression of prostate cancer nominated multiple subtype-specific cell-surface antigens. We specifically characterize FXYD3 and CEACAM5 as targets for immune-based therapies in PrAd and NEPC and provide preliminary evidence of the antigen-specific cytotoxic activity of CEACAM5-directed chimeric antigen receptor T cells in NEPC.